基于卷积神经网络的肾脏肿瘤 CT 图像分割技术

IF 3 4区 计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC International Journal of Imaging Systems and Technology Pub Date : 2024-07-17 DOI:10.1002/ima.23142
Cong Hu, Wenwen Jiang, Tian Zhou, Chunting Wan, Aijun Zhu
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引用次数: 0

摘要

肾肿瘤是人类最常见的肿瘤之一,目前主要的治疗方法是手术切除。CT 图像通常由专科医生手动分割,以便进行术前规划,但这可能会受到外科医生经验和技术的影响,而且耗时较长。由于肾脏肿瘤病变复杂,形态各异,分割难度大,本文提出了一种基于卷积神经网络的肾脏肿瘤 CT 图像自动分割方法,以解决肿瘤分割图像中最常见的边界模糊和假阳性问题。该方法准确度高、可靠性强,可用于辅助医生进行手术规划和诊断治疗,在一定程度上缓解了医疗压力。本文提出的EfficientNetV2-UNet分割模型包括特征提取器、重建网络和贝叶斯决策算法三大部分。首先,针对肿瘤假阳性现象,选用训练精度高、效率高的EfficientNetV2特征提取器作为骨干网络,通过降采样提取CT图像中肿瘤位置、形态、纹理等浅层特征。其次,在骨干网络的基础上设计重构网络,主要由转换块、解卷积块、卷积块和输出块组成。然后,构建上采样结构,逐步恢复特征图的空间分辨率,充分识别上下文信息,形成完整的编码-解码结构。通过在网络左右两侧叠加各级特征图通道,实现多尺度特征融合,防止细节丢失,进行精确的肿瘤分割。最后,针对分割后肿瘤的边缘模糊现象设计了贝叶斯决策算法,并在重建网络的输出上进行级联,结合原始 CT 图像和分割后图像的边缘特征进行概率估计,用于提高模型边缘分割的准确性。利用python将NII特殊格式的医学图像转换为Numpy矩阵格式,然后从KiTS19数据集中选取2000多张只包含肾脏肿瘤的CT图像作为模型的数据集,并将尺寸标准化为128 × 128,实验结果表明,该模型优于许多其他先进模型,具有良好的分割性能。
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Convolutional Neural Network-Based CT Image Segmentation of Kidney Tumours

Kidney tumours are one of the most common tumours in humans and the main current treatment is surgical removal. The CT images are usually manually segmented by a specialist for pre-operative planning, but this can be influenced by the surgeon's experience and skill and can be time-consuming. Due to the complex lesions and different morphologies of kidney tumours that make segmentation difficult, this article proposes a convolutional neural network-based automatic segmentation method for CT images of kidney tumours to address the most common problems of boundary blurring and false positives in tumour segmentation images. The method is highly accurate and reliable, and is used to assist doctors in surgical planning as well as diagnostic treatment, relieving medical pressure to a certain extent. The EfficientNetV2-UNet segmentation model proposed in this article includes three main parts: feature extractor, reconstruction network and Bayesian decision algorithm. Firstly, for the phenomenon of tumour false positives, the EfficientNetV2 feature extractor, which has high training accuracy and efficiency, is selected as the backbone network, which extracts shallow features such as tumour location, morphology and texture in the CT image by downsampling. Secondly, on the basis of the backbone network, the reconstruction network is designed, which mainly consists of conversion block, deconvolution block, convolution block and output block. Then, the up-sampling architecture is constructed to gradually recover the spatial resolution of the feature map, fully identify the contextual information and form a complete encoding–decoding structure. Multi-scale feature fusion is achieved by superimposing all levels of feature map channels on the left and right sides of the network, preventing the loss of details and performing accurate tumour segmentation. Finally, a Bayesian decision algorithm is designed for the edge blurring phenomenon of segmented tumours and cascaded over the output of the reconstruction network, combining the edge features of the original CT image and the segmented image for probability estimation, which is used to improve the accuracy of the model edge segmentation. Medical images in NII special format were converted to Numpy matrix format using python, and then more than 2000 CT images containing only kidney tumours were selected from the KiTS19 dataset as the dataset for the model, and the dimensions were standardised to 128 × 128, and the experimental results show that the model outperforms many other advanced models with good segmentation performance.

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来源期刊
International Journal of Imaging Systems and Technology
International Journal of Imaging Systems and Technology 工程技术-成像科学与照相技术
CiteScore
6.90
自引率
6.10%
发文量
138
审稿时长
3 months
期刊介绍: The International Journal of Imaging Systems and Technology (IMA) is a forum for the exchange of ideas and results relevant to imaging systems, including imaging physics and informatics. The journal covers all imaging modalities in humans and animals. IMA accepts technically sound and scientifically rigorous research in the interdisciplinary field of imaging, including relevant algorithmic research and hardware and software development, and their applications relevant to medical research. The journal provides a platform to publish original research in structural and functional imaging. The journal is also open to imaging studies of the human body and on animals that describe novel diagnostic imaging and analyses methods. Technical, theoretical, and clinical research in both normal and clinical populations is encouraged. Submissions describing methods, software, databases, replication studies as well as negative results are also considered. The scope of the journal includes, but is not limited to, the following in the context of biomedical research: Imaging and neuro-imaging modalities: structural MRI, functional MRI, PET, SPECT, CT, ultrasound, EEG, MEG, NIRS etc.; Neuromodulation and brain stimulation techniques such as TMS and tDCS; Software and hardware for imaging, especially related to human and animal health; Image segmentation in normal and clinical populations; Pattern analysis and classification using machine learning techniques; Computational modeling and analysis; Brain connectivity and connectomics; Systems-level characterization of brain function; Neural networks and neurorobotics; Computer vision, based on human/animal physiology; Brain-computer interface (BCI) technology; Big data, databasing and data mining.
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