喹氟灵(杀虫剂)。

Food safety (Tokyo, Japan) Pub Date : 2024-06-28 eCollection Date: 2024-06-01 DOI:10.14252/foodsafetyfscj.D-24-00009
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引用次数: 0

摘要

日本食品安全委员会(FSCJ)根据提交的文件对喹啉类杀菌剂喹氟灵(化学文摘社编号:861647-84-9)进行了风险评估。评估中使用的数据包括在植物(包括水稻和番茄)中的归宿、在农作物中的残留、在牲畜(山羊和鸡)中的归宿、在畜产品中的残留、在动物(大鼠)中的归宿、亚急性毒性(大鼠、小鼠和狗)、慢性毒性(狗)、慢性毒性/致癌性(大鼠)、致癌性(小鼠)、急性神经毒性(大鼠)、亚急性神经毒性(大鼠)、两代生殖毒性(大鼠)、发育毒性(大鼠和兔子)以及遗传毒性。FSCJ 规定每日允许摄入量为 0.03 毫克/千克体重/天,并根据无观测不良效应水平采用安全系数 100 后,规定急性参考剂量为 0.3 毫克/千克体重/天。
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Quinofumelin (Pesticides).

Food Safety Commission of Japan (FSCJ) conducted a risk assessment of quinofumelin (CAS No. 861647-84-9), a quinoline fungicide, based on submitted documents. The data used in the assessment are fate in plants (including paddy rice and tomatoes), residues in crops, fate in livestock (goats and chickens), residues in livestock products, fate in animals (rats), subacute toxicity (rats, mice, and dogs), chronic toxicity (dogs), combined chronic toxicity/carcinogenicity (rats), carcinogenicity (mice), acute neurotoxicity (rats), subacute neurotoxicity (rats), two-generation reproductive toxicity (rats), developmental toxicity (rats and rabbits), and genotoxicity. FSCJ specified an acceptable daily intake (ADI) of 0.03 mg/kg bw per day, and consequently specified an acute reference dose (ARfD) of 0.3 mg/kg bw per day after applying a safety factor of 100 based on the NOAEL.

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Cadmium (Third Edition) (Chemicals and Contaminants). Geographical Variation of Antimicrobial Resistance of Salmonella in Japanese Chicken. 3-Nitrooxypropanol (Feed Additives). Quinofumelin (Pesticides). Basic Principles for Setting MRLs for Pesticides in Food Commodities in Japan.
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