用于生物分子和治疗剂程序控制释放的多功能智能纳米生物聚合物:现代新兴系统概述

IF 1.9 4区 化学 Q2 CHEMISTRY, ORGANIC Mini-reviews in Organic Chemistry Pub Date : 2024-07-18 DOI:10.2174/0118756298304506240628062045
Zahra Mazidi, Hamid Reza Garshasbi, Seyed Morteza Naghib, Mojgan Heydari, M. R. Mozafari
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引用次数: 0

摘要

:普通给药的全身释放毒性会对人体的各种组织和器官产生不可逆的影响。使用对人体生理条件敏感的程序化生物聚合物进行靶向给药已引起广泛关注。这种方法有许多好处。生物学家和物理学家面临的一个重要挑战是,需要合适的生物聚合物作为药物载体,以实现程序化货物递送。总结这类材料对选择合适的材料很有帮助。生物聚合物领域取得的广泛进展和具备的多种能力使其在日常使用中日益增多,在其他材料中,本研究对生物聚合物进行了研究。本研究介绍了用于程序化给药的最重要聚合物。我们试图讨论这些材料在智能刺激敏感给药方面的有效特性、它们的优缺点、不同形式、如何将它们用作智能载体以及它们的吸收机制。
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Multifunctional Smart Nano Biopolymers for Programmed Controlled Release of Biomolecules and Therapeutic Agents: An Overview on Modern Emerging Systems
: The toxicity of systemic release in common drug delivery has irreversible effects on various tissues and organs of the body. The use of programmed biopolymers sensitive to the body's physiological conditions for targeted drug delivery has attracted extensive consideration. There are numerous benefits to this approach. The need for appropriate biopolymers for drug carriers suitable for programmed cargo delivery is a crucial challenge for biologists and physicists. Summarizing such materials can be very helpful in selecting the right materials. Extensive advances and many capabilities in the field of biopolymers have led to their increasing daily use, and among other materials, this research on biopolymers. In this study, the most important polymers for programmed drug delivery are introduced. We have tried to discuss the effective properties of materials in smart stimuli-sensitive drug delivery, their advantages and disadvantages, different forms, how to use them as a smart carrier, and their absorption mechanism.
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来源期刊
Mini-reviews in Organic Chemistry
Mini-reviews in Organic Chemistry 化学-有机化学
CiteScore
4.50
自引率
4.30%
发文量
116
审稿时长
>12 weeks
期刊介绍: Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges. The journal encourages submission of reviews on emerging fields of organic chemistry including: Bioorganic Chemistry Carbohydrate Chemistry Chemical Biology Chemical Process Research Computational Organic Chemistry Development of Synthetic Methodologies Functional Organic Materials Heterocyclic Chemistry Macromolecular Chemistry Natural Products Isolation And Synthesis New Synthetic Methodology Organic Reactions Organocatalysis Organometallic Chemistry Theoretical Organic Chemistry Polymer Chemistry Stereochemistry Structural Investigations Supramolecular Chemistry
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