嘧啶衍生物:最新发现及其对医学的影响

SABIU RABILU ABDULLAHI, ABUBAKAR MUHD SHAFI’I, SAPNA RAGHAV, MA’ARUF ABDULMUMIN MUHAMMAD
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引用次数: 0

摘要

嘧啶衍生物的多种生物功能和可能的治疗用途吸引了药物化学领域的大量研究。本综述重点介绍了基于嘧啶的分子在合成、生物评估和治疗用途方面的最新进展。本综述讨论了嘧啶衍生物在治疗癌症、传染病和代谢紊乱等一系列疾病中的重要作用,以及创新的合成方法和重要的药理学发现。为了全面介绍嘧啶衍生物的研究现状及其对未来药物开发的影响,本综述将对近期文献和案例研究进行分析。
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Pyrimidine derivatives: Recent discoveries and development towards its medicinal impact
Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyrimidine derivative research and its implications for upcoming medication development, this review will analyze recent literature and case studies.
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