{"title":"嘧啶衍生物:最新发现及其对医学的影响","authors":"SABIU RABILU ABDULLAHI, ABUBAKAR MUHD SHAFI’I, SAPNA RAGHAV, MA’ARUF ABDULMUMIN MUHAMMAD","doi":"10.30574/gscarr.2024.20.1.0248","DOIUrl":null,"url":null,"abstract":"Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyrimidine derivative research and its implications for upcoming medication development, this review will analyze recent literature and case studies.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"10 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pyrimidine derivatives: Recent discoveries and development towards its medicinal impact\",\"authors\":\"SABIU RABILU ABDULLAHI, ABUBAKAR MUHD SHAFI’I, SAPNA RAGHAV, MA’ARUF ABDULMUMIN MUHAMMAD\",\"doi\":\"10.30574/gscarr.2024.20.1.0248\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyrimidine derivative research and its implications for upcoming medication development, this review will analyze recent literature and case studies.\",\"PeriodicalId\":12791,\"journal\":{\"name\":\"GSC Advanced Research and Reviews\",\"volume\":\"10 9\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"GSC Advanced Research and Reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30574/gscarr.2024.20.1.0248\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"GSC Advanced Research and Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30574/gscarr.2024.20.1.0248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Pyrimidine derivatives: Recent discoveries and development towards its medicinal impact
Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyrimidine derivative research and its implications for upcoming medication development, this review will analyze recent literature and case studies.