自动调节概念的转变:对 "人类静态自动调节 "的评论。

IF 4.9 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Journal of Cerebral Blood Flow and Metabolism Pub Date : 2024-11-01 Epub Date: 2024-08-05 DOI:10.1177/0271678X241254676
Jurgen Ahr Claassen
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引用次数: 0

摘要

成像技术的进步改变了我们对大脑自动调节的认识。较早的成像技术提供的脑血流(CBF)测量值反映了 10-20 分钟内的平均 CBF。一个可追溯到 1959 年的重要发现是,CBF 在血压变化的极大范围内基本保持稳定。现代技术可以在心跳的时间范围内测量 CBF 的变化。矛盾的是,这些技术揭示了 CBF 的显著不稳定性。本评论试图调和这些看似矛盾的观察结果。
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Shifting concepts of autoregulation: Commentary to 'Static autoregulation in humans'.

Advances in imaging techniques have transformed our understanding of cerebral autoregulation. Older imaging techniques provided measurements of cerebral blood flow (CBF) that reflected the average CBF over a window of 10-20 minutes. A key finding, dating back to 1959, was that CBF remained more or less stable over a remarkably wide range of changes in blood pressure. Modern techniques can measure changes in CBF within the time frame of a heartbeat. They have revealed, paradoxically, a remarkable instability of CBF. This commentary attempts to reconcile these seemingly contradictory observations.

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来源期刊
Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism 医学-内分泌学与代谢
CiteScore
12.00
自引率
4.80%
发文量
300
审稿时长
3 months
期刊介绍: JCBFM is the official journal of the International Society for Cerebral Blood Flow & Metabolism, which is committed to publishing high quality, independently peer-reviewed research and review material. JCBFM stands at the interface between basic and clinical neurovascular research, and features timely and relevant research highlighting experimental, theoretical, and clinical aspects of brain circulation, metabolism and imaging. The journal is relevant to any physician or scientist with an interest in brain function, cerebrovascular disease, cerebral vascular regulation and brain metabolism, including neurologists, neurochemists, physiologists, pharmacologists, anesthesiologists, neuroradiologists, neurosurgeons, neuropathologists and neuroscientists.
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