{"title":"利用剪切波成像活体肌肉的肌内压力","authors":"","doi":"10.1016/j.jmps.2024.105834","DOIUrl":null,"url":null,"abstract":"<div><p>Shear wave elastography (SWE) is an innovative method that allows for the nondestructive and quantitative characterization of muscular mechanical properties. This method finds extensive utility in fields such as sports medicine, sports rehabilitation, and the diagnosis of muscle-related ailments. Existing studies have demonstrated the promise of SWE in probing intramuscular pressure (IMP), a factor intimately tied to muscular physiological functions and the onset of certain diseases. Nonetheless, there remains a lack of a SWE method grounded in an appropriate biomechanical model capable of effectively imaging IMP <em>in vivo</em>. Addressing this issue, we propose a shear wave imaging method relaying on a porohyperelastic model encompassing well-defined parameters for both muscular active behavior and intramuscular pressure. Drawing upon wave motion analysis, we establish a correlation between shear wave velocities and IMP in analytical form. This theoretical solution on one hand help understand the interplay between IMP and muscle active stress and the impact of muscle contraction on IMP. On the other hand, it enables us to develop an elastography method to assess IMP <em>in vivo</em>. We conducted a series of experiments to underscore the applicability of our theory and elastography method. <em>Ex vivo</em> experiments were performed on porcine muscles, while <em>in vivo</em> tests were carried out on human skeletal muscles. The results from the <em>ex vivo</em> tests validate the efficacy of our method. Meanwhile, the <em>in vivo</em> outcomes suggest that our approach holds potential to assess the variation of IMP with muscle fatigue and injuries, inspect intramuscular injections, and diagnose acute and chronic compartment syndrome.</p></div>","PeriodicalId":17331,"journal":{"name":"Journal of The Mechanics and Physics of Solids","volume":null,"pages":null},"PeriodicalIF":5.0000,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Imaging the intramuscular pressure of living muscles with shear waves\",\"authors\":\"\",\"doi\":\"10.1016/j.jmps.2024.105834\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Shear wave elastography (SWE) is an innovative method that allows for the nondestructive and quantitative characterization of muscular mechanical properties. This method finds extensive utility in fields such as sports medicine, sports rehabilitation, and the diagnosis of muscle-related ailments. Existing studies have demonstrated the promise of SWE in probing intramuscular pressure (IMP), a factor intimately tied to muscular physiological functions and the onset of certain diseases. Nonetheless, there remains a lack of a SWE method grounded in an appropriate biomechanical model capable of effectively imaging IMP <em>in vivo</em>. Addressing this issue, we propose a shear wave imaging method relaying on a porohyperelastic model encompassing well-defined parameters for both muscular active behavior and intramuscular pressure. Drawing upon wave motion analysis, we establish a correlation between shear wave velocities and IMP in analytical form. This theoretical solution on one hand help understand the interplay between IMP and muscle active stress and the impact of muscle contraction on IMP. On the other hand, it enables us to develop an elastography method to assess IMP <em>in vivo</em>. We conducted a series of experiments to underscore the applicability of our theory and elastography method. <em>Ex vivo</em> experiments were performed on porcine muscles, while <em>in vivo</em> tests were carried out on human skeletal muscles. The results from the <em>ex vivo</em> tests validate the efficacy of our method. Meanwhile, the <em>in vivo</em> outcomes suggest that our approach holds potential to assess the variation of IMP with muscle fatigue and injuries, inspect intramuscular injections, and diagnose acute and chronic compartment syndrome.</p></div>\",\"PeriodicalId\":17331,\"journal\":{\"name\":\"Journal of The Mechanics and Physics of Solids\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.0000,\"publicationDate\":\"2024-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of The Mechanics and Physics of Solids\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0022509624003004\",\"RegionNum\":2,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Mechanics and Physics of Solids","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022509624003004","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Imaging the intramuscular pressure of living muscles with shear waves
Shear wave elastography (SWE) is an innovative method that allows for the nondestructive and quantitative characterization of muscular mechanical properties. This method finds extensive utility in fields such as sports medicine, sports rehabilitation, and the diagnosis of muscle-related ailments. Existing studies have demonstrated the promise of SWE in probing intramuscular pressure (IMP), a factor intimately tied to muscular physiological functions and the onset of certain diseases. Nonetheless, there remains a lack of a SWE method grounded in an appropriate biomechanical model capable of effectively imaging IMP in vivo. Addressing this issue, we propose a shear wave imaging method relaying on a porohyperelastic model encompassing well-defined parameters for both muscular active behavior and intramuscular pressure. Drawing upon wave motion analysis, we establish a correlation between shear wave velocities and IMP in analytical form. This theoretical solution on one hand help understand the interplay between IMP and muscle active stress and the impact of muscle contraction on IMP. On the other hand, it enables us to develop an elastography method to assess IMP in vivo. We conducted a series of experiments to underscore the applicability of our theory and elastography method. Ex vivo experiments were performed on porcine muscles, while in vivo tests were carried out on human skeletal muscles. The results from the ex vivo tests validate the efficacy of our method. Meanwhile, the in vivo outcomes suggest that our approach holds potential to assess the variation of IMP with muscle fatigue and injuries, inspect intramuscular injections, and diagnose acute and chronic compartment syndrome.
期刊介绍:
The aim of Journal of The Mechanics and Physics of Solids is to publish research of the highest quality and of lasting significance on the mechanics of solids. The scope is broad, from fundamental concepts in mechanics to the analysis of novel phenomena and applications. Solids are interpreted broadly to include both hard and soft materials as well as natural and synthetic structures. The approach can be theoretical, experimental or computational.This research activity sits within engineering science and the allied areas of applied mathematics, materials science, bio-mechanics, applied physics, and geophysics.
The Journal was founded in 1952 by Rodney Hill, who was its Editor-in-Chief until 1968. The topics of interest to the Journal evolve with developments in the subject but its basic ethos remains the same: to publish research of the highest quality relating to the mechanics of solids. Thus, emphasis is placed on the development of fundamental concepts of mechanics and novel applications of these concepts based on theoretical, experimental or computational approaches, drawing upon the various branches of engineering science and the allied areas within applied mathematics, materials science, structural engineering, applied physics, and geophysics.
The main purpose of the Journal is to foster scientific understanding of the processes of deformation and mechanical failure of all solid materials, both technological and natural, and the connections between these processes and their underlying physical mechanisms. In this sense, the content of the Journal should reflect the current state of the discipline in analysis, experimental observation, and numerical simulation. In the interest of achieving this goal, authors are encouraged to consider the significance of their contributions for the field of mechanics and the implications of their results, in addition to describing the details of their work.