Axel Janson , Sebin Gracy , Philip E. Paré , Henrik Sandberg , Karl Henrik Johansson
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Competitive networked bi-virus spread: Existence of coexistence equilibria
The paper studies multi-competitive continuous-time epidemic processes. We consider the setting where two viruses are simultaneously prevalent, and the spread occurs due to individual-to-individual interaction. In such a setting, an individual is either not affected by any of the viruses, or infected by one and exactly one of the two viruses. One of the equilibrium points is the coexistence equilibrium, i.e., multiple viruses simultaneously infect separate fractions of the population. We provide a sufficient condition for the existence of a coexistence equilibrium. We identify a condition such that for certain pairs of spread matrices either every coexistence equilibrium lies on a line that is locally exponentially attractive, or there is no coexistence equilibrium. We then provide a condition that, for certain pairs of spread matrices, rules out the possibility of the existence of a coexistence equilibrium, and, as a consequence, establishes global asymptotic convergence to the endemic equilibrium of the dominant virus. Finally, we provide a mitigation strategy that employs one virus to ensure that the other virus is eradicated. The theoretical results are illustrated using simulations.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.