Conv-RGNN:用于心电图分类的高效卷积残差图神经网络

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computer methods and programs in biomedicine Pub Date : 2024-09-03 DOI:10.1016/j.cmpb.2024.108406
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引用次数: 0

摘要

背景和目的:心电图(ECG)分析是诊断心血管疾病(CVDs)的关键。在心电图分析中同时考虑时间和空间特征对于改善心血管疾病的自动诊断非常重要。随着深度学习的不断发展,基于心电图的心血管疾病自动诊断取得了重大进展。目前大多数研究通常将 12 导联心电图信号视为欧几里得空间中的同步序列,主要侧重于提取时间特征,而忽略了 12 导联之间的空间关系。然而,使用非欧几里得数据结构可以更自然地表示 12 导联心电图电极的空间分布,从而使导联之间的关系更符合其内在特征:本研究提出了一种用于心电图分类的创新方法--卷积残差图神经网络(Conv-RGNN)。第一步是将 12 导联心电图分割成 12 个单导联心电图,然后将这些单导联心电图映射到图中的节点,通过空间连接捕捉不同导联之间的关系,从而形成 12 导联心电图图。然后将该图作为 Conv-RGNN 的输入。具有位置关注机制的卷积神经网络用于提取时间序列信息,并选择性地整合上下文信息,以增强不同位置的语义特征。使用残差图神经网络提取 12 导联心电图图的空间特征:实验结果表明,Conv-RGNN 在两个多标签数据集和一个单标签数据集中具有很强的竞争力,在参数效率、推理速度、模型性能和鲁棒性方面都表现出了卓越的性能:本文提出的 Conv-RGNN 为资源受限环境下的智能诊断提供了一种前景广阔的可行方法。
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Conv-RGNN: An efficient Convolutional Residual Graph Neural Network for ECG classification

Background and objective:

Electrocardiogram (ECG) analysis is crucial in diagnosing cardiovascular diseases (CVDs). It is important to consider both temporal and spatial features in ECG analysis to improve automated CVDs diagnosis. Significant progress has been made in automated CVDs diagnosis based on ECG with the continuous development of deep learning. Current most researches often treat 12-lead ECG signals as synchronous sequences in Euclidean space, focusing primarily on extracting temporal features while overlooking the spatial relationships among the 12-lead. However, the spatial distribution of 12-lead ECG electrodes can be more naturally represented using non-Euclidean data structures, which makes the relationships among leads more consistent with their intrinsic characteristics.

Methods:

This study proposes an innovative method, Convolutional Residual Graph Neural Network (Conv-RGNN), for ECG classification. The first step is to segment the 12-lead ECG into twelve single-lead ECG, which are then mapped to nodes in a graph that captures the relationships between the different leads through spatial connections, resulting in the 12-lead ECG graph. The graph is then used as input for Conv-RGNN. A convolutional neural network with a position attention mechanism is used to extract temporal sequence information and selectively integrate contextual information to enhance semantic features at different positions. The spatial features of the 12-lead ECG graph are extracted using the residual graph neural network.

Results:

The experimental results indicate that Conv-RGNN is highly competitive in two multi-label datasets and one single-label dataset, demonstrating exceptional parameter efficiency, inference speed, model performance, and robustness.

Conclusion:

The Conv-RGNN proposed in this paper offer a promising and feasible approach for intelligent diagnosis in resource-constrained environments.

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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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