Christine Happle, Markus Hoffmann, Amy Kempf, Inga Nehlmeier, Metodi V. Stankov, Noemi Calderon Hampel, Torsten Witte, Stefan Pöhlmann, Georg M. N. Behrens, Alexandra Dopfer-Jablonka
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Humoral Immunity after mRNA Omicron JN.1 Vaccination
In late June 2024, the European Medicines Agency (EMA) recommended market authorization for a monovalent COVID-19 mRNA-vaccine based on JN.1 spike. We assessed immune responses in n=42 health-care workers (median age 47 years, interquartile range, IQR 19·5 years, 48% male), who in August 2024 were vaccinated with 30 μg of the updated mRNA omicron JN.1 vaccine (bretovameran, BioNTech/Pfizer, Mainz, Germany). Humoral immune responses were analyzed directly prior to and 13 days after vaccination.
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