作为呼吸道合胞病毒支气管炎严重程度标志的病毒长期脱落

Raí André Silva Watanabe, Filipe Nishiyama, Larissa Lyra, Bruno Sanchez Camargo, Luciano Kleber de Souza Luna, Danielle Dias Conte, Ana Helena Perosa, Nancy Cristina Junqueira Bellei
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摘要

背景和目的 呼吸道合胞病毒(RSV)是大多数儿童急性病毒性支气管炎(AVB)的病原体。RSV 亚型、病毒载量和病毒合并感染等因素与严重疾病的关系尚存在争议。本研究旨在描述 2 岁以下急性病毒性支气管炎患儿体内 RSV 病毒载量的动态变化,包括首次病毒载量、高峰病毒载量、病毒衰减以及与严重疾病之间可能存在的关联。
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Prolonged viral shedding as a marker of severity in respiratory syncytial virus bronchiolitis
Background and Objectives Respiratory syncytial virus (RSV) is responsible for most cases of acute viral bronchiolitis (AVB) in childhood. The association of factors such as RSV subtype, viral load, and viral coinfection with severe disease is controversial. The objective is to describe the viral load dynamics of RSV in children under 2 years with AVB, including the first viral load, peak viral load, viral decay, and any possible association with severe disease.
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