生物医学应用中的降解机制和镁合金保护涂层分析综述

IF 1.6 4区 材料科学 Q2 Materials Science Transactions of The Indian Institute of Metals Pub Date : 2024-08-28 DOI:10.1007/s12666-024-03424-7
C. Vinothkumar, G. Rajyalakshmi
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引用次数: 0

摘要

镁合金具有生物相容性、降解能力和机械性能等独特特性,是各种医疗设备和植入物的理想选择。然而,镁合金的快速降解和相关挑战限制了其广泛应用。本研究利用体外和体内环境,对镁合金与各种涂层接触时的腐蚀行为进行了深入分析。综述的重点是了解降解机制、影响腐蚀的因素以及由此产生的后果。此外,它还探讨了作为控制降解有效手段的涂层和金属成分,以及表面处理和腐蚀管理方法。为了增强镁合金的降解行为、生物活性和生物相容性,建议采用涉及涂层技术(如 HA 涂层、LDH、CaP 和二氧化钛涂层)的多步骤方法。这些涂层在改善镁合金的外部特性方面已显示出巨大的潜力。此外,使用多功能涂层能非常有效地为可生物降解植入物的应用创造安全且具有生物活性的基底,在生物医学工程领域具有巨大潜力。
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An Analytical Review on the Degradation Mechanisms and Magnesium Alloy Protective Coatings in Biomedical Applications

Unique characteristics such as biocompatibility, degradation capability, and mechanical properties have positioned magnesium alloys as highly favorable choices for use in various medical devices and implants. However, their rapid degradation and associated challenges have limited their widespread use. This study conducts a thorough analysis into the corrosion behavior of magnesium alloys when open to various coatings, using both in vitro and in vivo environments. The review focuses on understanding the degradation mechanisms, factors influencing corrosion, and the resulting consequences. Additionally, it explores the composition of coatings and metals as effective means to control degradation, along with surface treatment and corrosion management methods. To enhance the degrading behavior, bioactivity, and biocompatibility of magnesium alloys, a multistep approach involving coating techniques such as HA coating, LDH, CaP, and titanium dioxide coating is recommended. These coatings have shown significant potential in improving the exterior properties of Mg alloys. Furthermore, using multifunctional coatings is extremely effective in creating secure and bioactive substrates for the application of biodegradable implants, demonstrating significant potential in the field of biomedical engineering.

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来源期刊
Transactions of The Indian Institute of Metals
Transactions of The Indian Institute of Metals Materials Science-Metals and Alloys
CiteScore
2.60
自引率
6.20%
发文量
3
期刊介绍: Transactions of the Indian Institute of Metals publishes original research articles and reviews on ferrous and non-ferrous process metallurgy, structural and functional materials development, physical, chemical and mechanical metallurgy, welding science and technology, metal forming, particulate technologies, surface engineering, characterization of materials, thermodynamics and kinetics, materials modelling and other allied branches of Metallurgy and Materials Engineering. Transactions of the Indian Institute of Metals also serves as a forum for rapid publication of recent advances in all the branches of Metallurgy and Materials Engineering. The technical content of the journal is scrutinized by the Editorial Board composed of experts from various disciplines of Metallurgy and Materials Engineering. Editorial Advisory Board provides valuable advice on technical matters related to the publication of Transactions.
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