Hongjun Zhu, Tongtong Deng, Shan Hu, Xianyu Ying, Hui Wang
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Palladium Catalyzed Direct Ortho C‐H Acylation of 4‐Phenylquinoline using Methylarenes as Acylation Reagents
A simple ortho‐acylation of 4‐phenylquinazoline by a Pd‐catalyzed oxidative C–H activation was developed, with moderate yields, in which no prefunctionalized methylarenes were used as acylation reagents. Moreover, this methodology tolerates a wide range of functional groups. Radical scavenging experiments indicate that the acylation involves a benzoyl radical pathway.
期刊介绍：
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.
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