{"title":"微合成技术是微生物菌种追踪的强大前沿。","authors":"Peiwen Cai, Tal Korem","doi":"10.1016/j.crmeth.2024.100862","DOIUrl":null,"url":null,"abstract":"<p><p>Genomic diversity within species can be driven by both point mutations and larger structural variations, but so far, strain-tracking approaches have focused mostly on the former. In a recent issue of Nature Biotechnology, Ley and colleagues<sup>1</sup> introduce SynTracker, a tool designed for scalable strain tracking with microsynteny in low-coverage metagenomic settings.</p>","PeriodicalId":29773,"journal":{"name":"Cell Reports Methods","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440041/pdf/","citationCount":"0","resultStr":"{\"title\":\"Microsynteny is a powerful front for microbial strain tracking.\",\"authors\":\"Peiwen Cai, Tal Korem\",\"doi\":\"10.1016/j.crmeth.2024.100862\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Genomic diversity within species can be driven by both point mutations and larger structural variations, but so far, strain-tracking approaches have focused mostly on the former. In a recent issue of Nature Biotechnology, Ley and colleagues<sup>1</sup> introduce SynTracker, a tool designed for scalable strain tracking with microsynteny in low-coverage metagenomic settings.</p>\",\"PeriodicalId\":29773,\"journal\":{\"name\":\"Cell Reports Methods\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440041/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Reports Methods\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.crmeth.2024.100862\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Reports Methods","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.crmeth.2024.100862","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Microsynteny is a powerful front for microbial strain tracking.
Genomic diversity within species can be driven by both point mutations and larger structural variations, but so far, strain-tracking approaches have focused mostly on the former. In a recent issue of Nature Biotechnology, Ley and colleagues1 introduce SynTracker, a tool designed for scalable strain tracking with microsynteny in low-coverage metagenomic settings.
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