系统观察胰腺癌患者:通过研究肝脏预测转移

IF 40.8 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Signal Transduction and Targeted Therapy Pub Date : 2024-09-27 DOI:10.1038/s41392-024-01964-4
Susanne Roth, Christoph Michalski, Jörg D. Hoheisel
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引用次数: 0

摘要

在最近发表于《自然医学》(Nature Medicine)上的一篇论文中,Bojmar 等人描述了他们为预测胰腺导管腺癌(PDAC)在原发肿瘤切除后的转移进展所做的精心努力1。然而,他们并没有研究肿瘤,而是研究了在原发肿瘤切除过程中从似乎仍未受影响的肝脏中收集的活检样本中的几种分子、细胞和代谢特征,这表明以系统方式观察癌症具有巨大的、但仍被忽视的生物医学潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A systemic look at pancreatic cancer patients: Predicting metastasis by studying the liver

In a recent paper published in Nature Medicine, Bojmar et al. describe an elaborate effort toward predicting the metastatic progress of pancreatic ductal adenocarcinoma (PDAC) after primary tumour resection.1 Instead of investigating the tumour, however, they studied several molecular, cellular, and metabolic features in biopsy samples from the seemingly still unaffected liver, which were collected during resection of the primary tumour, demonstrating the large and still neglected biomedical potential of looking at cancer in a systemic manner.

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来源期刊
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy Biochemistry, Genetics and Molecular Biology-Genetics
CiteScore
44.50
自引率
1.50%
发文量
384
审稿时长
5 weeks
期刊介绍: Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy. Scope: The journal covers research on major human diseases, including, but not limited to: Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.
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