癫痫患者治疗结果回顾:癫痫发作控制和药物副作用。

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_246_24
P Naveen, G Sarala, D Manoj Chandra, Riddhiman Dutta, Vimal Satodiya, Rangraze Imran, Pritee Rajkumar Pandey
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引用次数: 0

摘要

背景:癫痫的治疗需要在控制发作和减少药物副作用之间取得平衡。这篇回顾性综述研究了癫痫患者的治疗结果,重点关注癫痫发作控制和药物相关不良反应:回顾性审查了 2017 年至 2022 年期间在三级医疗中心接受治疗的癫痫患者的病历。收集并分析人口统计学特征、癫痫发作控制情况、用药方案和副作用等数据:结果:共纳入200名受试者。60%的受试者完全摆脱了癫痫发作,30%的受试者减少了癫痫发作频率,10%的受试者没有改善或恶化。提供的抗癫痫药物种类对处方副作用有很大影响(P < 0.05),X 药物比 Y 药物更容易引起头晕(P = 0.02)。老年人比年轻人更容易出现倦怠感(P = 0.03):本综述为癫痫治疗结果提供了宝贵的见解,强调了个性化管理策略的必要性,以优化癫痫发作控制,同时最大限度地减少与药物相关的不良反应。
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Retrospective Review of Treatment Outcomes in Epilepsy Patients: Seizure Control and Medication Side Effects.

Background: Epilepsy management requires balancing seizure control with minimizing medication side effects. This retrospective review examines treatment outcomes in epilepsy patients, focusing on seizure control and medication-related adverse effects.

Methods: Medical records of epilepsy subjects treated tertiary care center between 2017 and 2022 were retrospectively reviewed. Data on demographic characteristics, seizure control, medication regimen, and side effects were collected and analyzed.

Results: A total of 200 subjects were included. Sixty percent of subjects achieved total seizure independence, 30% reduced seizure frequency, and 10% did not improve or deteriorate. The kind of antiepileptic medicine provided substantially affects prescription side effects (P < 0.05), with drug X causing more dizziness than drug Y (P = 0.02). Elderly individuals were more likely to suffer weariness than younger ones (P = 0.03).

Conclusion: This review provides valuable insights into epilepsy treatment outcomes, emphasizing the need for personalized management strategies to optimize seizure control while minimizing medication-related adverse effects.

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