三维数字光工艺生物打印:解决器官制造问题的尖端平台

IF 8.7 1区 医学 Q1 ENGINEERING, BIOMEDICAL Materials Today Bio Pub Date : 2024-10-02 DOI:10.1016/j.mtbio.2024.101284
Yun Geun Jeong , James J. Yoo , Sang Jin Lee , Moon Suk Kim
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引用次数: 0

摘要

再生医学取代或恢复人体受损器官的功能,该领域的研究进展迅速。这些进展为人工器官的开发带来了重要的创新。近年来,三维(3D)生物打印技术已成为再生医学领域一项前景广阔的技术。在各种技术中,数字光处理(DLP)三维生物打印技术因其能够精确制造高分辨率、结构复杂的人造器官而脱颖而出。本综述探讨了 DLP 打印设备、生物墨水和光引发剂的类型和使用趋势。在此基础上,探讨了 DLP 生物打印技术在创建人体器官精密微结构以及再生医学中组织和器官模型再生方面的应用。最后,讨论了基于 DLP 的生物打印技术,特别是再生医学中的精密打印应用所面临的挑战和未来展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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3D digital light process bioprinting: Cutting-edge platforms for resolution of organ fabrication
Research in the field of regenerative medicine, which replaces or restores the function of human damaged organs is advancing rapidly. These advances are fostering important innovations in the development of artificial organs. In recent years, three-dimensional (3D) bioprinting has emerged as a promising technology for regenerative medicine applications. Among various techniques, digital light process (DLP) 3D bioprinting stands out for its ability to precisely create high-resolution, structurally complex artificial organs. This review explores the types and usage trends of DLP printing equipment, bioinks, and photoinitiators. Building on this foundation, the applications of DLP bioprinting for creating precise microstructures of human organs and for regenerating tissue and organ models in regenerative medicine are examined. Finally, challenges and future perspectives regarding DLP-based bioprinting, particularly for precision printing applications in regenerative medicine, are discussed.
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来源期刊
CiteScore
8.30
自引率
4.90%
发文量
303
审稿时长
30 days
期刊介绍: Materials Today Bio is a multidisciplinary journal that specializes in the intersection between biology and materials science, chemistry, physics, engineering, and medicine. It covers various aspects such as the design and assembly of new structures, their interaction with biological systems, functionalization, bioimaging, therapies, and diagnostics in healthcare. The journal aims to showcase the most significant advancements and discoveries in this field. As part of the Materials Today family, Materials Today Bio provides rigorous peer review, quick decision-making, and high visibility for authors. It is indexed in Scopus, PubMed Central, Emerging Sources, Citation Index (ESCI), and Directory of Open Access Journals (DOAJ).
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