知道何时停止:MICL 自我调节中性粒细胞 NETosis

IF 2.9 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Biochemistry Biochemistry Pub Date : 2024-10-14 DOI:10.1038/s41422-024-01037-9
Hanjoo Brian Shim, Justin François Deniset, Paul Kubes
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引用次数: 0

摘要

在最近发表于《自然》(Nature)的一项研究中,Malamud 等人确定了中性粒细胞 MICL 如何识别中性粒细胞胞外捕获物(NET)。这种识别抑制了中性粒细胞的进一步活化和 NET 的产生,从而防止了炎症的恶性循环。
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Knowing when to stop: MICL self-regulates neutrophil NETosis

In a recent study published in Nature, Malamud et al. identified how neutrophil MICL recognizes neutrophil extracellular traps (NETs). This recognition suppresses further neutrophil activation and NET production, thereby preventing a vicious cycle of inflammation.

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来源期刊
Biochemistry Biochemistry
Biochemistry Biochemistry 生物-生化与分子生物学
CiteScore
5.50
自引率
3.40%
发文量
336
审稿时长
1-2 weeks
期刊介绍: Biochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function, and encompasses the fields of chemical biology, synthetic biology, disease biology, cell biology, nucleic acid biology, neuroscience, structural biology, and biophysics. In addition to traditional Research Articles, Biochemistry also publishes Communications, Viewpoints, and Perspectives, as well as From the Bench articles that report new methods of particular interest to the biological chemistry community.
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