早期诊断和介入性青光眼。

IF 2.3 Q2 OPHTHALMOLOGY Therapeutic Advances in Ophthalmology Pub Date : 2024-10-13 eCollection Date: 2024-01-01 DOI:10.1177/25158414241287431
Ticiana De Francesco, Jason Bacharach, Oluwatosin Smith, Manjool Shah
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引用次数: 0

摘要

青光眼的治疗模式正开始从依赖局部用药的被动式方法转变为利用手术干预的主动式方法。越来越多风险较低的微创手术,如激光小梁成形术、微创青光眼手术和手术药物等,推动了青光眼介入治疗的发展。与所有青光眼干预措施一样,这些青光眼干预措施的一个共同特点是需要早期、及时和准确的诊断。本综述总结了青光眼诊断方面的新进展和即将取得的进展。其中包括基于家庭的眼压测量技术和工艺、新型视野平台、基于摄影和光学相干断层扫描的可视化以及人工智能应用。它们还包括线粒体黄蛋白荧光成像、凋亡视网膜细胞检测、集电极通道可视化和基因检测等新兴技术。这些诊断模式有可能规避传统诊断方法的局限性。通过提高获取有价值的青光眼数据的频率和可行性,更快速地检测疾病和进展情况,这些诊断方法可实现青光眼治疗的干预性方法,从而改善对患者的护理。
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Early diagnostics and interventional glaucoma.

The glaucoma treatment paradigm is starting to change from a more reactive approach that relies on topical medications to a more proactive approach that leverages procedural interventions. This evolution toward interventional glaucoma has been enabled by a growing array of lower-risk minimally invasive procedures such as laser trabeculoplasty, minimally invasive glaucoma surgery, and procedural pharmaceuticals. A common feature of these glaucoma interventions-as with all glaucoma interventions-is the need for early, prompt, and accurate diagnosis. The present review summarizes new and upcoming developments in glaucoma diagnostics. These include technologies and techniques for home-based intraocular pressure measurement, novel visual field platforms, photography- and optical coherence tomography-based visualization, and artificial intelligence applications. They also include emerging technologies such as mitochondrial flavoprotein fluorescence imaging, detection of apoptosing retinal cells, collector channel visualization, and genetic testing. These diagnostic modalities have the potential to circumvent the limitations of traditional diagnostic methods. By increasing the frequency and feasibility of obtaining valuable glaucoma data with more rapid detection of disease and progression, these diagnostics may enable an interventional approach to glaucoma treatment for the betterment of patient care.

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来源期刊
CiteScore
4.50
自引率
0.00%
发文量
44
审稿时长
12 weeks
期刊最新文献
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