M Frenkel, S Iyer, R Antar, A Akram, S M Lee, J Lichtenberger, B Shin
{"title":"双能减影射线摄影(DESR):肺结节检测的系统回顾和荟萃分析。","authors":"M Frenkel, S Iyer, R Antar, A Akram, S M Lee, J Lichtenberger, B Shin","doi":"10.1016/j.crad.2024.09.015","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the literature to compare the accuracy, sensitivity, and specificity of dual-energy subtraction radiography (DESR) with conventional radiography (CR) in the detection of pulmonary nodules. To our knowledge, no meta-analysis has been conducted to compare DESR with CR.</p><p><strong>Material and methods: </strong>The authors searched Pubmed using the terms \"Dual-energy subtraction radiography,\" and \"Dual-Energy Chest Radiography.\" Only studies comparing the detection of pulmonary nodules between DESR and CR were included. Studies utilizing artificial intelligence were excluded. The primary study outcomes analyzed were the mean difference of receiver operating characteristic area under the curve (ROC AUC), mean difference of sensitivity, and mean difference of specificity.</p><p><strong>Results: </strong>Twenty-three studies between 1994 and 2022 were included. Of these twenty-three, eighteen reported ROC AUC statistics. The difference between DESR ROC AUC (mean = 0.7702, SD = 0.1361) and CR ROC AUC (mean = 0.7106, SD = 0.1183) was 0.0597 (P<0.001). Sensitivity data was reported for thirteen of the twenty-three selected studies. The difference between DESR sensitivity (mean = 0.5753, SD = 0.1546) and CR sensitivity (mean = 0.4391, SD = 0.1007) was 0.136 (P<0.001). Specificity data were reported for ten of the twenty-three selected studies. The difference between DESR specificity (mean = 0.753, SD = 0.1575) and CR specificity (mean = 0.764, SD = 0.1168) was -0.011 (P=0.767). This was not statistically significant.</p><p><strong>Conclusions: </strong>DESR showed superior sensitivity and ROC AUC values compared with CR in detecting pulmonary nodules. There was no difference in specificity.</p>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dual-energy subtraction radiography (DESR): a systematic review and meta-analysis of pulmonary nodule detection.\",\"authors\":\"M Frenkel, S Iyer, R Antar, A Akram, S M Lee, J Lichtenberger, B Shin\",\"doi\":\"10.1016/j.crad.2024.09.015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study examined the literature to compare the accuracy, sensitivity, and specificity of dual-energy subtraction radiography (DESR) with conventional radiography (CR) in the detection of pulmonary nodules. To our knowledge, no meta-analysis has been conducted to compare DESR with CR.</p><p><strong>Material and methods: </strong>The authors searched Pubmed using the terms \\\"Dual-energy subtraction radiography,\\\" and \\\"Dual-Energy Chest Radiography.\\\" Only studies comparing the detection of pulmonary nodules between DESR and CR were included. Studies utilizing artificial intelligence were excluded. The primary study outcomes analyzed were the mean difference of receiver operating characteristic area under the curve (ROC AUC), mean difference of sensitivity, and mean difference of specificity.</p><p><strong>Results: </strong>Twenty-three studies between 1994 and 2022 were included. Of these twenty-three, eighteen reported ROC AUC statistics. The difference between DESR ROC AUC (mean = 0.7702, SD = 0.1361) and CR ROC AUC (mean = 0.7106, SD = 0.1183) was 0.0597 (P<0.001). Sensitivity data was reported for thirteen of the twenty-three selected studies. The difference between DESR sensitivity (mean = 0.5753, SD = 0.1546) and CR sensitivity (mean = 0.4391, SD = 0.1007) was 0.136 (P<0.001). Specificity data were reported for ten of the twenty-three selected studies. The difference between DESR specificity (mean = 0.753, SD = 0.1575) and CR specificity (mean = 0.764, SD = 0.1168) was -0.011 (P=0.767). This was not statistically significant.</p><p><strong>Conclusions: </strong>DESR showed superior sensitivity and ROC AUC values compared with CR in detecting pulmonary nodules. There was no difference in specificity.</p>\",\"PeriodicalId\":10695,\"journal\":{\"name\":\"Clinical radiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.crad.2024.09.015\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.crad.2024.09.015","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Dual-energy subtraction radiography (DESR): a systematic review and meta-analysis of pulmonary nodule detection.
Purpose: This study examined the literature to compare the accuracy, sensitivity, and specificity of dual-energy subtraction radiography (DESR) with conventional radiography (CR) in the detection of pulmonary nodules. To our knowledge, no meta-analysis has been conducted to compare DESR with CR.
Material and methods: The authors searched Pubmed using the terms "Dual-energy subtraction radiography," and "Dual-Energy Chest Radiography." Only studies comparing the detection of pulmonary nodules between DESR and CR were included. Studies utilizing artificial intelligence were excluded. The primary study outcomes analyzed were the mean difference of receiver operating characteristic area under the curve (ROC AUC), mean difference of sensitivity, and mean difference of specificity.
Results: Twenty-three studies between 1994 and 2022 were included. Of these twenty-three, eighteen reported ROC AUC statistics. The difference between DESR ROC AUC (mean = 0.7702, SD = 0.1361) and CR ROC AUC (mean = 0.7106, SD = 0.1183) was 0.0597 (P<0.001). Sensitivity data was reported for thirteen of the twenty-three selected studies. The difference between DESR sensitivity (mean = 0.5753, SD = 0.1546) and CR sensitivity (mean = 0.4391, SD = 0.1007) was 0.136 (P<0.001). Specificity data were reported for ten of the twenty-three selected studies. The difference between DESR specificity (mean = 0.753, SD = 0.1575) and CR specificity (mean = 0.764, SD = 0.1168) was -0.011 (P=0.767). This was not statistically significant.
Conclusions: DESR showed superior sensitivity and ROC AUC values compared with CR in detecting pulmonary nodules. There was no difference in specificity.
期刊介绍:
Clinical Radiology is published by Elsevier on behalf of The Royal College of Radiologists. Clinical Radiology is an International Journal bringing you original research, editorials and review articles on all aspects of diagnostic imaging, including:
• Computed tomography
• Magnetic resonance imaging
• Ultrasonography
• Digital radiology
• Interventional radiology
• Radiography
• Nuclear medicine
Papers on radiological protection, quality assurance, audit in radiology and matters relating to radiological training and education are also included. In addition, each issue contains correspondence, book reviews and notices of forthcoming events.