Tengyun Guo , Xiaoshu Wang , Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang, Rui Xu
{"title":"热建模及其在治疗大脑中动脉分叉动脉瘤和相关缺血性并发症中的作用","authors":"Tengyun Guo , Xiaoshu Wang , Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang, Rui Xu","doi":"10.1016/j.tsep.2024.102985","DOIUrl":null,"url":null,"abstract":"<div><div>Bifurcated aneurysm of cerebral artery is a common cerebrovascular disease, which can easily lead to serious ischemic complications. Traditional treatments face challenges of risk and effectiveness. Therefore, it is particularly important to explore new therapeutic strategies. In recent years, the application of thermal modeling techniques in medical biological systems has provided a new perspective for the analysis of hemodynamics and tissue thermal response. The purpose of this study was to investigate the role of heat model in the treatment of bifurcated cerebral artery aneurysms and their associated ischemic complications, and to evaluate its potential value in understanding disease mechanisms and optimizing treatment protocols. In this study, a three-dimensional thermal model was used to simulate the heat conduction and blood flow characteristics of the bifurcated parts of cerebral arteries. Combined with the clinical data of patients, the influence of the thermal model on the formation mechanism of aneurysms and the prognosis evaluation of ischemic complications were analyzed through numerical calculation and experimental verification. Compare the performance of different treatment methods in thermal models. The thermal model shows that the temperature distribution at the aneurysm site is closely related to the blood flow velocity, and the local temperature increase may promote thrombosis and lead to ischemic complications. The treatment regimen optimized by the thermal model showed significant improvement in the simulation, reducing the risk of complications and improving hemodynamic parameters. Heat model can reveal the dynamic relationship between blood flow and temperature in the study of cerebral artery bifurcation aneurysm, and provide theoretical support for clinical treatment.</div></div>","PeriodicalId":23062,"journal":{"name":"Thermal Science and Engineering Progress","volume":"55 ","pages":"Article 102985"},"PeriodicalIF":5.1000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Thermal modeling and its role in management of bifurcation aneurysms and associated ischemic complications in the middle cerebral artery\",\"authors\":\"Tengyun Guo , Xiaoshu Wang , Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang, Rui Xu\",\"doi\":\"10.1016/j.tsep.2024.102985\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Bifurcated aneurysm of cerebral artery is a common cerebrovascular disease, which can easily lead to serious ischemic complications. Traditional treatments face challenges of risk and effectiveness. Therefore, it is particularly important to explore new therapeutic strategies. In recent years, the application of thermal modeling techniques in medical biological systems has provided a new perspective for the analysis of hemodynamics and tissue thermal response. The purpose of this study was to investigate the role of heat model in the treatment of bifurcated cerebral artery aneurysms and their associated ischemic complications, and to evaluate its potential value in understanding disease mechanisms and optimizing treatment protocols. In this study, a three-dimensional thermal model was used to simulate the heat conduction and blood flow characteristics of the bifurcated parts of cerebral arteries. Combined with the clinical data of patients, the influence of the thermal model on the formation mechanism of aneurysms and the prognosis evaluation of ischemic complications were analyzed through numerical calculation and experimental verification. Compare the performance of different treatment methods in thermal models. The thermal model shows that the temperature distribution at the aneurysm site is closely related to the blood flow velocity, and the local temperature increase may promote thrombosis and lead to ischemic complications. The treatment regimen optimized by the thermal model showed significant improvement in the simulation, reducing the risk of complications and improving hemodynamic parameters. Heat model can reveal the dynamic relationship between blood flow and temperature in the study of cerebral artery bifurcation aneurysm, and provide theoretical support for clinical treatment.</div></div>\",\"PeriodicalId\":23062,\"journal\":{\"name\":\"Thermal Science and Engineering Progress\",\"volume\":\"55 \",\"pages\":\"Article 102985\"},\"PeriodicalIF\":5.1000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Thermal Science and Engineering Progress\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2451904924006036\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENERGY & FUELS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Thermal Science and Engineering Progress","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451904924006036","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENERGY & FUELS","Score":null,"Total":0}
Thermal modeling and its role in management of bifurcation aneurysms and associated ischemic complications in the middle cerebral artery
Bifurcated aneurysm of cerebral artery is a common cerebrovascular disease, which can easily lead to serious ischemic complications. Traditional treatments face challenges of risk and effectiveness. Therefore, it is particularly important to explore new therapeutic strategies. In recent years, the application of thermal modeling techniques in medical biological systems has provided a new perspective for the analysis of hemodynamics and tissue thermal response. The purpose of this study was to investigate the role of heat model in the treatment of bifurcated cerebral artery aneurysms and their associated ischemic complications, and to evaluate its potential value in understanding disease mechanisms and optimizing treatment protocols. In this study, a three-dimensional thermal model was used to simulate the heat conduction and blood flow characteristics of the bifurcated parts of cerebral arteries. Combined with the clinical data of patients, the influence of the thermal model on the formation mechanism of aneurysms and the prognosis evaluation of ischemic complications were analyzed through numerical calculation and experimental verification. Compare the performance of different treatment methods in thermal models. The thermal model shows that the temperature distribution at the aneurysm site is closely related to the blood flow velocity, and the local temperature increase may promote thrombosis and lead to ischemic complications. The treatment regimen optimized by the thermal model showed significant improvement in the simulation, reducing the risk of complications and improving hemodynamic parameters. Heat model can reveal the dynamic relationship between blood flow and temperature in the study of cerebral artery bifurcation aneurysm, and provide theoretical support for clinical treatment.
期刊介绍:
Thermal Science and Engineering Progress (TSEP) publishes original, high-quality research articles that span activities ranging from fundamental scientific research and discussion of the more controversial thermodynamic theories, to developments in thermal engineering that are in many instances examples of the way scientists and engineers are addressing the challenges facing a growing population – smart cities and global warming – maximising thermodynamic efficiencies and minimising all heat losses. It is intended that these will be of current relevance and interest to industry, academia and other practitioners. It is evident that many specialised journals in thermal and, to some extent, in fluid disciplines tend to focus on topics that can be classified as fundamental in nature, or are ‘applied’ and near-market. Thermal Science and Engineering Progress will bridge the gap between these two areas, allowing authors to make an easy choice, should they or a journal editor feel that their papers are ‘out of scope’ when considering other journals. The range of topics covered by Thermal Science and Engineering Progress addresses the rapid rate of development being made in thermal transfer processes as they affect traditional fields, and important growth in the topical research areas of aerospace, thermal biological and medical systems, electronics and nano-technologies, renewable energy systems, food production (including agriculture), and the need to minimise man-made thermal impacts on climate change. Review articles on appropriate topics for TSEP are encouraged, although until TSEP is fully established, these will be limited in number. Before submitting such articles, please contact one of the Editors, or a member of the Editorial Advisory Board with an outline of your proposal and your expertise in the area of your review.