使用迪克森技术进行基于脂肪-水信号的电特性断层扫描

IF 5.6 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC IEEE Transactions on Instrumentation and Measurement Pub Date : 2024-10-30 DOI:10.1109/TIM.2024.3485405
Yinhao Ren;Kecheng Yuan;Guofang Xu;Chunyou Ye;Feng Liu;Bensheng Qiu;Xiang Nan;Jijun Han
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引用次数: 0

摘要

这项研究旨在利用 Dixon 技术提出一种基于脂肪水定量的电特性断层扫描(FW-EPT),从而提高电特性断层扫描(EPT)的准确性,并为从目前的临床路由模式中获取电特性(EPs)提供一种可行的方法。在 64 MHz 频率下建立了九个不同脂肪水(FW)含量的人体肝脏模拟模型。使用开口同轴探针法测量了 EPs,并通过 Dixon 扫描获得了 FW 信号。随后,建立了三组拟合模型:F-EPs,只考虑脂肪信息;W-EPs,只考虑水信息;FW-EPs,同时考虑脂肪和水信息。为了评估这些模型的准确性,对两名健康受试者进行了 FW-EPT 实验,并以文献值作为参考基准对实验结果进行了评估。实验结果表明,FW-EPT 拟合模型的准确度最高。与文献值相比,1.5T 磁共振成像(MRI)下人体肝脏电导率和相对介电常数的平均相对误差分别低于 2.89% 和 5.37%。临床人体磁共振(MR)实验的扫描时间约为 22 秒。FW-EPT 能够更快、更高分辨率、更精确地对人体肝脏组织中的 EPs 进行成像。这项研究的结果为临床 EPT 提供了新的见解。
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Fat-Water Signal-Based Electrical Properties Tomography Using the Dixon Technique
This study aimed to improve the accuracy of electrical properties tomography (EPT) by proposing a fat-water quantification-based EPT (FW-EPT) using the Dixon technique and provided a feasible approach for obtaining electrical properties (EPs) from current clinical routing modalities. Nine human liver-mimicking phantoms were built with varying fat-water (FW) content at 64 MHz. The EPs were measured using the open-ended coaxial probe method, and an FW signal was obtained through Dixon scanning. Subsequently, three sets of fit models were established: F-EPs, considering only fat information; W-EPs, considering only water information; and FW-EPs, considering both fat and water information. To assess the accuracy of these models, FW-EPT experiments were conducted on two healthy subjects, and the results were evaluated using literature values as a reference benchmark. Experiments showed that the FW-EPs fitted model offered the best accuracy. Compared with the literature values, the average relative errors for human liver conductivity and relative permittivity at 1.5T magnetic resonance imaging (MRI) were lower than 2.89% and 5.37%, respectively. The scanning time for clinical human magnetic resonance (MR) experiments was approximately 22 s. FW-EPT enabled faster, higher resolution, and more precise imaging of EPs in human liver tissue. The findings of this study offered new insights for clinical EPT.
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来源期刊
IEEE Transactions on Instrumentation and Measurement
IEEE Transactions on Instrumentation and Measurement 工程技术-工程:电子与电气
CiteScore
9.00
自引率
23.20%
发文量
1294
审稿时长
3.9 months
期刊介绍: Papers are sought that address innovative solutions to the development and use of electrical and electronic instruments and equipment to measure, monitor and/or record physical phenomena for the purpose of advancing measurement science, methods, functionality and applications. The scope of these papers may encompass: (1) theory, methodology, and practice of measurement; (2) design, development and evaluation of instrumentation and measurement systems and components used in generating, acquiring, conditioning and processing signals; (3) analysis, representation, display, and preservation of the information obtained from a set of measurements; and (4) scientific and technical support to establishment and maintenance of technical standards in the field of Instrumentation and Measurement.
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