心脏再生导致浦肯野纤维网和心室传导发生改变

IF 9.4 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Nature cardiovascular research Pub Date : 2024-11-12 DOI:10.1038/s44161-024-00549-2
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引用次数: 0

摘要

在新生小鼠中,新生儿心肌梗死后,来自心室小梁的细胞参与了收缩心肌的修复,但这一过程会导致过量产生未成熟的浦肯野纤维,形成增生网络,并导致心室传导发生改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Cardiac regeneration leads to altered Purkinje fiber network and ventricular conduction
In newborn mice, after a neonatal cardiac infarction, cells derived from the ventricular trabeculae participate in the repair of the contractile myocardium, but this process results in excessive production of immature Purkinje fibers that form a hyperplastic network and lead to altered ventricular conduction.
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