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引用次数: 0
摘要
背景：炎症和内皮功能障碍是慢性疾病（包括心血管疾病和相关死亡率）的重要风险因素：本系统综述和荟萃分析旨在评估两种流行饮食模式--补充橄榄油的地中海饮食（MED）和低脂饮食（LFD）--对成年人炎症和内皮功能相关因素的影响：在以下在线数据库中搜索了截至 2024 年 8 月 7 日发表的相关研究：PubMed/Medline、Scopus、Clarivate Analytics Web of Science、Cochrane Central Register of Controlled Trials 和 Google Scholar。两名独立研究人员根据资格标准对研究进行了筛选：数据分析：效应大小以 Hedges' g 表示，95% CIs。共有 16 项符合条件的试验和 20 个效应大小被纳入分析。这项荟萃分析表明，与低脂饮食相比，补充橄榄油的 MED 饮食显著改善了所有研究指标，但 E 选择素除外，据报道，E 选择素的下降幅度较低，且不显著：现有证据表明，与低脂饮食相比，补充橄榄油的 MED 饮食能明显改善成年人的炎症和血清内皮功能：系统综述注册：PROSPERO 注册号CRD42023485718。
Effect of the Mediterranean Diet Supplemented With Olive Oil Versus the Low-Fat Diet on Serum Inflammatory and Endothelial Indexes Among Adults: A Systematic Review and Meta-analysis of Clinical Controlled Trials.
Context: Inflammation and endothelial dysfunction are important risk factors for chronic diseases, including cardiovascular diseases and related mortality.
Objective: This systematic review and meta-analysis aimed to assess the effects of 2 popular dietary patterns-a Mediterranean (MED) diet supplemented with olive oil and a low-fat diet (LFD)-on factors related to inflammation and endothelial function in adults.
Data sources and data extraction: The following online databases were searched for related studies published until August 7, 2024: PubMed/Medline, Scopus, Clarivate Analytics Web of Science, Cochrane Central Register of Controlled Trials, and Google Scholar. Two independent researchers selected the studies based on the eligibility criteria.
Data analysis: The effect sizes were expressed as Hedges' g with 95% CIs. A total of 16 eligible trials with 20 effect sizes were included in the analyses. This meta-analysis revealed that the MED diet supplemented with olive oil significantly improved all of the indicators of the study compared with the LFD, except in the case of E-selectin, in which a low and nonsignificant decrease was reported.
Conclusion: Available evidence suggests that a MED diet supplemented with olive oil compared with the LFD significantly improves inflammation and serum endothelial function in adults.
期刊介绍：
Nutrition Reviews is a highly cited, monthly, international, peer-reviewed journal that specializes in the publication of authoritative and critical literature reviews on current and emerging topics in nutrition science, food science, clinical nutrition, and nutrition policy. Readers of Nutrition Reviews include nutrition scientists, biomedical researchers, clinical and dietetic practitioners, and advanced students of nutrition.
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