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Nutritional interventions in prison settings: a scoping review. 监狱环境中的营养干预:范围界定审查。
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-02-01 DOI: 10.1093/nutrit/nuae011
Claudia Vetrani, Ludovica Verde, Antinea Ambretti, Giovanna Muscogiuri, Antonio Maria Pagano, Luciano Lucania, Annamaria Colao, Luigi Barrea

Background: Mounting evidence has shown that incarceration can affect the health and well-being of individuals and increase the risk of noncommunicable diseases (NCDs). Diet quality is known to be one of the main determinants of risk of NCDs, and dietary changes are the first approach used in primary care to reduce the incidence of NCDs.

Objective: This scoping review aimed to summarize the evidence for (1) the diet quality of inmates, and (2) the effect of nutritional intervention in prison systems. In addition, we aimed to describe limitations in the current literature and to suggest potential future research areas.

Method: A systematic search was performed in 2 databases (PubMed and Web of Science) using predefined search terms and covering the period May 2023 to June 2023. Additionally, reference lists from the retrieved studies were hand-searched to identify any additional relevant publications. The identified literature was screened based on defined search strategies, criteria, and research questions defined using the PICo (population or problem, interest, and context) framework. The review was conducted referring to the PRISMA-ScR and the PICo framework.

Results: A total of 19 studies out of 63 initially identified records were included in this review (11 cross-sectional evaluations and 9 intervention-based studies). In almost all studies, assessment of the diet quality of menus showed the menus to be nutritionally adequate, except for having a higher-than-recommended intake of total energy, saturated fatty acids, sodium, cholesterol, and sugar. In addition, some studies reported a lower-than-recommended intake of fiber, magnesium, potassium, vitamins D, E, and A, and omega-3 fatty acids. Nutritional interventions were mainly planned in the form of workshops, seminars, and written material to deliver information on healthy dietary choices. Although no significant changes in inmates' dietary choices were observed in any of the studies, a high participation rate was detected.

Conclusion: Inmates might require additional prevention intervention to reduce their susceptibility to cardiometabolic diseases by virtue of their isolation from community facilities. Interventions should be tailored to the characteristics of prison settings and inmates to increase adherence to nutritional recommendations.

背景:越来越多的证据表明,监禁会影响个人的健康和福祉,增加罹患非传染性疾病(NCD)的风险。众所周知,膳食质量是非传染性疾病风险的主要决定因素之一,而改变膳食是初级保健中用于降低非传染性疾病发病率的首要方法:本次范围界定综述旨在总结以下方面的证据:(1)囚犯的饮食质量;(2)监狱系统中营养干预的效果。此外,我们还旨在描述当前文献的局限性,并提出未来潜在的研究领域:使用预定义的检索词在两个数据库(PubMed 和 Web of Science)中进行了系统检索,检索期为 2023 年 5 月至 2023 年 6 月。此外,还对检索到的研究的参考文献目录进行了人工搜索,以确定任何其他相关出版物。根据定义的检索策略、标准和使用 PICo(人群或问题、兴趣和背景)框架定义的研究问题,对确定的文献进行了筛选。审查参照 PRISMA-ScR 和 PICo 框架进行:在 63 项初步确定的记录中,共有 19 项研究(11 项横断面评估和 9 项基于干预的研究)被纳入本综述。几乎所有的研究都对菜单的饮食质量进行了评估,结果表明,除了总能量、饱和脂肪酸、钠、胆固醇和糖的摄入量高于建议摄入量之外,菜单的营养都是充足的。此外,一些研究报告称,纤维、镁、钾、维生素 D、E 和 A 以及欧米茄-3 脂肪酸的摄入量低于建议摄入量。营养干预措施主要计划以讲习班、研讨会和书面材料的形式提供有关健康饮食选择的信息。虽然在所有研究中都没有观察到囚犯的饮食选择有明显变化,但参与率很高:结论:由于与社区设施隔绝,囚犯可能需要额外的预防干预措施来降低他们对心脏代谢疾病的易感性。干预措施应根据监狱环境和囚犯的特点量身定制,以提高对营养建议的依从性。
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引用次数: 0
Orthorexia nervosa in dietitians and dietetics students-prevalence, risk factors, and interventions: a scoping review using a systematic approach. 营养师和营养学学生中的厌食症--患病率、风险因素和干预措施:采用系统方法进行的范围界定综述。
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-02-01 DOI: 10.1093/nutrit/nuae009
Chloe Ephrem, Rana Rizk, Danielle Saadeh, Souheil Hallit, Sahar Obeid, Carolien Martijn

Context: Orthorexia nervosa (ON) is characterized by compulsive behaviors and increased concerns about healthful eating. Dietitians appear to be especially vulnerable to ON, and it is still debatable whether the disordered eating behaviors motivate individuals to enroll in nutrition programs, or whether these behaviors result from an exaggerated preoccupation with healthy eating triggered during their nutrition studies.

Objective: The aim was to provide an overview of the present state of knowledge about the prevalence, risk factors, and interventions addressing ON among dietitians and dietetics students. More specifically, it was examined whether dietitians and dietetics students differ from students attending different education programs or other health professionals with regard to the severity and risk factors of ON, and whether the extent of ON changes during the progression in the nutrition education years of study.

Data sources: MEDLINE (Ovid), PubMed, EMBASE (Ovid), PsycInfo (EBSCO), CINAHL (EBSCO), Cochrane, ProQuest Central, CABI, ProQuest Dissertations, Google Scholar, ScienceDirect, and SpringerLink were searched on May 8, 2021, and updated on November 12, 2022.

Data extraction: Records were screened for eligibility; study characteristics, methodology, and findings of included articles were extracted; and the methodological quality assessed using the AXIS tool. Each step was preceded by a calibration exercise and conducted independently and in duplicate by pairs of 2 reviewers. Any disagreements were resolved through discussions.

Data analysis: A narrative synthesis was performed, whereby the characteristics, methodologies, and results of included studies were compared.

Conclusions: Results were inconclusive; yet, a general status of the relatively "high" prevalence of ON among dietitians and dietetics students was established, stressing the need for systematic research to understand and mitigate orthorexic tendencies in this group. It is still too early to answer questions pertaining to prevalence, risk factors, interventions, and differences between dietetics students and other majors when it comes to severity and progress of ON throughout the continuing years of study, or between dietitians and other professional groups.

Systematic review registration: Open Science Framework Identifier: DOI 10.17605/OSF.IO/BY5KF.

背景:神经性厌食症(ON)的特征是强迫行为和对健康饮食的日益关注。营养师似乎特别容易患上 "神经性厌食症",目前仍有争议的是,饮食失调行为是促使个人报名参加营养计划的原因,还是在营养学学习期间对健康饮食的过分关注导致了这些行为:目的:本研究旨在概述有关营养师和营养学学生中ON的流行率、风险因素和干预措施的知识现状。更具体地说,该研究考察了营养师和营养学专业学生与不同教育项目的学生或其他卫生专业人员在 "营养不良 "的严重程度和风险因素方面是否存在差异,以及 "营养不良 "的程度是否会随着营养教育学习年限的增加而发生变化:于2021年5月8日检索了MEDLINE(Ovid)、PubMed、EMBASE(Ovid)、PsycInfo(EBSCO)、CINAHL(EBSCO)、Cochrane、ProQuest Central、CABI、ProQuest Dissertations、Google Scholar、ScienceDirect和SpringerLink,并于2022年11月12日进行了更新:筛选符合条件的记录;提取纳入文章的研究特征、方法和结果;使用 AXIS 工具评估方法学质量。每个步骤之前都要进行校准,并由两名审稿人独立重复进行。数据分析:数据分析:进行了叙述性综合,对纳入研究的特点、方法和结果进行了比较:结论:研究结果尚无定论,但已确定营养师和营养学学生中ON发病率相对 "较高 "的总体状况,强调有必要开展系统性研究,以了解和缓解这一群体的矫形倾向。要回答营养学学生和其他专业学生在整个持续学习年限内ON的严重程度和进展情况,或营养师和其他专业群体之间在ON的流行率、风险因素、干预措施、差异等方面的问题,还为时尚早:系统综述注册:开放科学框架标识符:doi 10.17605/osf.io/by5kf。
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引用次数: 0
eHealth, family-based interventions, and multilevel approaches to pediatric weight management: a scoping review. 儿科体重管理的电子健康、家庭干预和多层次方法:范围界定综述。
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-02-01 DOI: 10.1093/nutrit/nuad160
Sarah T Henes, Sarah A Stotz, Sandra E Riggs, Hsuan-Mein Yang

Objective: This scoping review examines the current literature on technology-based, eHealth interventions that integrate community and clinical approaches for family-based pediatric weight management.

Background: Telehealth and eHealth interventions for weight management are increasingly commonplace; however, it is unclear in the current literature how family-based, pediatric, healthy-weight interventions integrate technology. Additionally, multilevel approaches to address childhood obesity, including working with clinical and community partners, are currently considered best practice and within the socioecological framework for sustainability of outcomes. Little is known how current family based pediatric healthy weight interventions integrate eHealth and multi-level approaches.

Methods: Guided by Arksey and O'Malley's scoping review framework, a scoping literature review was conducted. Four databases were searched to identify studies conducted between 2010 and 2022 that addressed multilevel, family-based, pediatric weight management interventions that also integrated technology. Studies were excluded that did not include at least 2 of the 4 components and that did not include technology to some degree.

Results: A total of 15 articles were included in the scoping review. All articles included some type of technology in the intervention. Twelve articles included a family-based approach, and only 1 article fully used a holistic approach to family-based, pediatric weight management that included technology and integrated clinical and community approaches to address the complexity of childhood obesity.

Conclusions: There are several family-based, pediatric weight management interventions that incorporate an eHealth component. There is a gap in the literature about programs that use both technology and integrate multilevel clinical and community approaches for treatment. Additionally, gaps exist in information about adolescent, family-based, weight management interventions, and there are opportunities for nutrition and dietetic professionals to become more involved with technological and multilevel approaches in family-based pediatric weight management.

摘要本范围综述研究了目前有关基于技术的电子健康干预措施的文献,这些干预措施整合了社区和临床方法,用于以家庭为基础的儿科体重管理:背景:针对体重管理的远程保健和电子保健干预措施越来越普遍;然而,目前的文献还不清楚以家庭为基础的儿科健康体重干预措施是如何整合技术的。此外,解决儿童肥胖问题的多层次方法,包括与临床和社区伙伴合作,目前被认为是最佳实践,也是成果可持续性的社会生态框架。目前以家庭为基础的儿科健康体重干预是如何整合电子健康和多层次方法的,人们对此知之甚少:在 Arksey 和 O'Malley 的范围审查框架指导下,进行了范围文献审查。对四个数据库进行了检索,以确定 2010 年至 2022 年期间进行的有关多层次、以家庭为基础、同时整合了技术的儿科体重管理干预措施的研究。结果显示,共收录了 15 篇文章:共有 15 篇文章被纳入范围审查。所有文章都在干预措施中包含了某种技术。有 12 篇文章采用了以家庭为基础的方法,只有 1 篇文章完全采用了以家庭为基础的儿科体重管理综合方法,其中包括技术以及临床和社区综合方法,以应对儿童肥胖的复杂性:结论:有几种以家庭为基础的儿科体重管理干预措施包含了电子健康元素。关于既使用技术又整合了多层次临床和社区治疗方法的项目,文献中还存在空白。此外,有关青少年、基于家庭的体重管理干预措施的信息也存在空白,营养和饮食专业人员有机会更多地参与基于家庭的儿科体重管理中的技术和多层次方法。
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引用次数: 0
Short-Chain Fatty Acids and Preeclampsia: A Scoping Review. 短链脂肪酸与先兆子痫:范围界定综述。
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-02-01 DOI: 10.1093/nutrit/nuae057
Heather J Zhao, Yingan Chen, Tiange Liu, Kristen McArthur, Noel T Mueller

Background: Preeclampsia (PE) is a pregnancy-associated hypertension disorder with high morbidity and mortality. Short-chain fatty acids (SCFAs)-molecules produced by gut microbes-have been associated with hypertension, yet their relation to PE remains uncertain.

Objectives: The aim was to review existing human studies that examined associations of the major SCFAs (acetate, propionate, butyrate) in pregnancy with PE development.

Methods: Two reviewers independently searched online databases (EMBASE, PubMed, Web of Science, and Cochrane Database of Systematic Reviews) in January 2024 using the following terms: "short-chain fatty acids," "acetic acid," "butyric acid," "propionic acid," and "preeclampsia." The final set of included studies had to report associations of SCFAs with PE, be peer-reviewed, be written in English, and be conducted in humans.

Results: The abstracts of 907 studies were screened; 43 underwent full-text screening and 11 (1318 total participants, 352 with PE) were included in the final review. All studies used a case-control design. SCFAs were measured in a range of biospecimens (eg, serum, plasma, feces, placentas, and amniotic fluid) that were collected at distinct time points in pregnancy. All 7 studies that investigated butyrate found that it was lower in PE cases than in controls, with 6 of these showing statistical significance (P < .05). Five studies showed that acetate was significantly lower in individuals with PE compared with healthy individuals, while 1 study found that acetate was significantly higher in PE cases. One study reported significantly higher propionate among PE cases vs controls, while 2 studies reported significantly lower propionate levels in PE cases. The nuance in results for acetate and propionate may owe to reasons such as differences in distributions of population characteristics associated with SCFA level and PE or type of PE (early vs late).

Conclusion: Current epidemiologic evidence, which derives only from case-control studies, suggests that SCFAs, particularly butyrate (protective), in pregnancy are related to the development of PE. Large-cohort studies are warranted to investigate the temporality and potential causality of these associations.

背景:子痫前期(PE)是一种与妊娠相关的高血压疾病,发病率和死亡率都很高。短链脂肪酸(SCFAs)--肠道微生物产生的分子--与高血压有关,但它们与子痫前期的关系仍不确定:目的:回顾现有的人类研究,这些研究探讨了妊娠期主要 SCFAs(醋酸酯、丙酸酯、丁酸酯)与 PE 发生的关系:两位审稿人于 2024 年 1 月使用以下术语独立检索了在线数据库(EMBASE、PubMed、Web of Science 和 Cochrane 系统综述数据库):"短链脂肪酸"、"乙酸"、"丁酸"、"丙酸 "和 "子痫前期"。最终纳入的研究必须报告 SCFA 与子痫前期的关系、经过同行评审、以英语撰写且在人类中进行:对 907 项研究的摘要进行了筛选;对 43 项研究进行了全文筛选,最终有 11 项研究(共 1318 名参与者,其中 352 人患有 PE)被纳入最终综述。所有研究均采用病例对照设计。SCFAs在一系列生物样本(如血清、血浆、粪便、胎盘和羊水)中进行了测量,这些样本是在孕期的不同时间点采集的。对丁酸盐进行调查的所有 7 项研究均发现,PE 患者的丁酸盐含量低于对照组,其中 6 项研究的结果具有统计学意义(P 结 论):目前的流行病学证据(仅来自病例对照研究)表明,妊娠期的 SCFAs,尤其是丁酸盐(保护性),与 PE 的发生有关。有必要进行大型队列研究,以调查这些关联的时间性和潜在因果关系。
{"title":"Short-Chain Fatty Acids and Preeclampsia: A Scoping Review.","authors":"Heather J Zhao, Yingan Chen, Tiange Liu, Kristen McArthur, Noel T Mueller","doi":"10.1093/nutrit/nuae057","DOIUrl":"10.1093/nutrit/nuae057","url":null,"abstract":"<p><strong>Background: </strong>Preeclampsia (PE) is a pregnancy-associated hypertension disorder with high morbidity and mortality. Short-chain fatty acids (SCFAs)-molecules produced by gut microbes-have been associated with hypertension, yet their relation to PE remains uncertain.</p><p><strong>Objectives: </strong>The aim was to review existing human studies that examined associations of the major SCFAs (acetate, propionate, butyrate) in pregnancy with PE development.</p><p><strong>Methods: </strong>Two reviewers independently searched online databases (EMBASE, PubMed, Web of Science, and Cochrane Database of Systematic Reviews) in January 2024 using the following terms: \"short-chain fatty acids,\" \"acetic acid,\" \"butyric acid,\" \"propionic acid,\" and \"preeclampsia.\" The final set of included studies had to report associations of SCFAs with PE, be peer-reviewed, be written in English, and be conducted in humans.</p><p><strong>Results: </strong>The abstracts of 907 studies were screened; 43 underwent full-text screening and 11 (1318 total participants, 352 with PE) were included in the final review. All studies used a case-control design. SCFAs were measured in a range of biospecimens (eg, serum, plasma, feces, placentas, and amniotic fluid) that were collected at distinct time points in pregnancy. All 7 studies that investigated butyrate found that it was lower in PE cases than in controls, with 6 of these showing statistical significance (P < .05). Five studies showed that acetate was significantly lower in individuals with PE compared with healthy individuals, while 1 study found that acetate was significantly higher in PE cases. One study reported significantly higher propionate among PE cases vs controls, while 2 studies reported significantly lower propionate levels in PE cases. The nuance in results for acetate and propionate may owe to reasons such as differences in distributions of population characteristics associated with SCFA level and PE or type of PE (early vs late).</p><p><strong>Conclusion: </strong>Current epidemiologic evidence, which derives only from case-control studies, suggests that SCFAs, particularly butyrate (protective), in pregnancy are related to the development of PE. Large-cohort studies are warranted to investigate the temporality and potential causality of these associations.</p>","PeriodicalId":19469,"journal":{"name":"Nutrition reviews","volume":" ","pages":"e683-e693"},"PeriodicalIF":5.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward Sustainable Diets-Interventions and Perceptions Among Adolescents: A Scoping Review. 实现可持续饮食--青少年的干预措施和观念:范围审查。
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-02-01 DOI: 10.1093/nutrit/nuae052
Adeline R Lanham, Jolieke C van der Pols

Adolescence is an important life stage during which shifts toward more healthy and sustainable diets can be promoted. Adolescents have increasing influence over their food choices, informed by their developing personal knowledge and values, affecting long-term dietary behaviors into adulthood. The recent literature regarding adolescents' (1) perceptions of environmentally sustainable diets and (2) interventions to support adolescents to eat sustainably was reviewed in this study. We reviewed published literature that focused on adolescent participants and their perceptions of, or interventions to support, sustainable dietary habits. Five electronic databases were searched to include studies published since 2012 that met the inclusion criteria, including reporting of participants aged between 11 and 18 years, reporting on adolescents' perceptions of sustainable diets or interventions implemented to improve the sustainability of adolescents' diets, and framed in the context of sustainability. Data were extracted, including study and participant characteristics, methodology, and results in relation to each of the 2 research focus areas. Twenty-eight articles were included in the review. Findings suggest that adolescents' understanding of what constitutes sustainable eating is poor. Adolescents who had previously received education regarding sustainable diets valued nature and health, or were from a rural or indigenous community, were more likely to value environmentally sustainable-food choices. Interventions which target adolescents' understanding of and aspiration to make sustainable-food choices appears to improve their attitudes toward sustainable food, whereas interventions to increase the availability of sustainable foods improved the environmental sustainability of adolescents' dietary intake. Multicomponent, tailored, and community-based interventions were most effective; however, the long-term effect of these interventions remains unclear. More research is needed in low- and middle-income countries, with consideration of adolescents' level of autonomy in food choice in local food environments and the long-term effectiveness of interventions. Systematic Review Registration: Open Science Framework identifier osf.io/h3jz6.

青少年时期是一个重要的人生阶段,在这一阶段可以促进他们向更健康、更可持续的饮食习惯转变。青少年在个人知识和价值观形成的过程中,对食物选择的影响越来越大,从而影响到成年后的长期饮食行为。本研究回顾了有关青少年(1)对环境可持续饮食的看法和(2)支持青少年可持续饮食的干预措施的最新文献。我们查阅了已发表的文献,这些文献主要关注青少年参与者及其对可持续饮食习惯的看法或支持可持续饮食习惯的干预措施。我们检索了五个电子数据库,以纳入自 2012 年以来发表的符合纳入标准的研究,这些标准包括报告 11 至 18 岁的参与者、报告青少年对可持续饮食的看法或为改善青少年饮食的可持续性而实施的干预措施,并以可持续性为背景。提取的数据包括与两个研究重点领域相关的研究和参与者特征、方法和结果。综述共收录了 28 篇文章。研究结果表明,青少年对什么是可持续饮食的理解并不深刻。以前接受过可持续饮食教育、重视自然和健康的青少年,或者来自农村或土著社区的青少年,更有可能重视环境可持续食品的选择。针对青少年对可持续食品选择的理解和愿望而采取的干预措施似乎能改善他们对可持续食品的态度,而增加可持续食品供应量的干预措施则能改善青少年饮食摄入的环境可持续性。多成分、量身定制和基于社区的干预措施最为有效;然而,这些干预措施的长期效果仍不明确。需要在中低收入国家开展更多研究,同时考虑青少年在当地食品环境中选择食品的自主程度以及干预措施的长期有效性。系统综述注册:开放科学框架标识符osf.io/h3jz6。
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引用次数: 0
Ultra-Processed Food Intakes and Health Outcomes in Adults Older Than 60 Years: A Systematic Review.
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-01-31 DOI: 10.1093/nutrit/nuae223
Fay A Shahatah, Tom R Hill, Andrea Fairley, Anthony W Watson

Context: Relationships between ultraprocessed food (UPF) intakes and health have been well described in adults, but evidence of these relationships in older adults is rather limited. Demographic shifts in aging emphasize the importance of understanding the role of diet in maintaining health during later life.

Objective: The aim of this systematic review was to identify health outcomes associated with UPF consumption in those aged ≥60 years.

Data sources: The Medline, Web of Science, Scopus, and Embase databases were searched from inception until June 2023, using search terms representing UPF and any health outcome. Observational studies restricted to individuals aged ≥60 years using the Nova food classification were included. Articles were screened independently by 2 researchers using PECOS inclusion criteria.

Data extraction: Two-thirds of the studies in the present review were prospective cohort studies (n = 4) and the rest were cross-sectional (n = 2). The number of participants ranged from 652 to 2713 across the 6 studies. The mean age of participants ranged between 67 and 73 years.

Data analysis: In the prospective cohort studies, the highest consumption of UPF was associated with incident frailty, incident dyslipidemia, renal function decline, and abdominal obesity. For cross-sectional studies, the highest intake of UPF was associated with negative outcomes similar to young and middle-aged cohorts, with the addition of nutritional frailty and worse cognitive performance.

Conclusions: Currently, the limited understanding of how high UPF intakes could be associated with negative health outcomes for older adults influences the ability to inform policy and practice recommendations. More research is required owing to the very limited number of studies, specifically in older adults.

Systematic review registration: PROSPERO registration no. CRD42023442783.

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引用次数: 0
Effects of the Curcuminoid and Non-Curcuminoid Compounds of Turmeric on the Gut Microbiome and Inflammation: Potential Use in the Treatment and Prevention of Disease.
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-01-28 DOI: 10.1093/nutrit/nuae221
Claire Kacena

The gut microbiome is a complex system that directly interacts with and influences many systems in the body. This delicate balance of microbiota plays an important role in health and disease and is highly influenced by lifestyle factors and the surrounding environment. As further research emerges, understanding the full potential of the gut microbiome and the impact of using nutraceuticals to positively influence its function may open the door to greater therapeutic outcomes in the treatment and prevention of disease. Curcumin, a bioactive compound derived from the turmeric rhizome, has been studied in depth for its influence on human health as a potent anti-inflammatory and antioxidant properties. However, the therapeutic activity of curcumin is limited by its low oral bioavailability. While most available research has primarily focused on the curcuminoid compounds of turmeric, the non-curcuminoid compounds hold promise to offer therapeutic benefits while synergistically enhancing the bioavailability of curcumin and supporting the gut microbiome. This review summarizes current knowledge of the relationship between the gut and the various systems within the body, and how dysbiosis, or disruption in the gut microbial balance, leads to inflammation and increased risk of chronic disease. The review also summarizes recent research that focuses on the bioactivity of both the curcuminoid and non-curcuminoid compounds that comprise the whole turmeric root and their synergistic role in enhancing bioavailability to support a healthy gut microbiome and promising use in the treatment and prevention of disease.

{"title":"Effects of the Curcuminoid and Non-Curcuminoid Compounds of Turmeric on the Gut Microbiome and Inflammation: Potential Use in the Treatment and Prevention of Disease.","authors":"Claire Kacena","doi":"10.1093/nutrit/nuae221","DOIUrl":"https://doi.org/10.1093/nutrit/nuae221","url":null,"abstract":"<p><p>The gut microbiome is a complex system that directly interacts with and influences many systems in the body. This delicate balance of microbiota plays an important role in health and disease and is highly influenced by lifestyle factors and the surrounding environment. As further research emerges, understanding the full potential of the gut microbiome and the impact of using nutraceuticals to positively influence its function may open the door to greater therapeutic outcomes in the treatment and prevention of disease. Curcumin, a bioactive compound derived from the turmeric rhizome, has been studied in depth for its influence on human health as a potent anti-inflammatory and antioxidant properties. However, the therapeutic activity of curcumin is limited by its low oral bioavailability. While most available research has primarily focused on the curcuminoid compounds of turmeric, the non-curcuminoid compounds hold promise to offer therapeutic benefits while synergistically enhancing the bioavailability of curcumin and supporting the gut microbiome. This review summarizes current knowledge of the relationship between the gut and the various systems within the body, and how dysbiosis, or disruption in the gut microbial balance, leads to inflammation and increased risk of chronic disease. The review also summarizes recent research that focuses on the bioactivity of both the curcuminoid and non-curcuminoid compounds that comprise the whole turmeric root and their synergistic role in enhancing bioavailability to support a healthy gut microbiome and promising use in the treatment and prevention of disease.</p>","PeriodicalId":19469,"journal":{"name":"Nutrition reviews","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting Ketone Body Metabolism Improves Cardiac Function and Hemodynamics in Patients With Heart Failure: A Systematic Review and Meta-Analysis.
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-01-28 DOI: 10.1093/nutrit/nuae179
Tingting Lv, Chunyan Liu, Shitian Guo, Menglu Wu, Xiang Wang, Ziyi Zhang, Jiedong Zhou, Yiying Yao, Zeyu Shen, Juntao Yang, Shijia Sun, Zheng Liu, Jufang Chi

Context: The impacts of elevated ketone body levels on cardiac function and hemodynamics in patients with heart failure (HF) remain unclear.

Objective: The effects of ketone intervention on these parameters in patients with HF were evaluated quantitatively in this meta-analysis.

Data sources: We searched the PubMed, Cochrane Library, and Embase databases for relevant studies published from inception to April 13, 2024. Ketone therapy included ketone ester and β-hydroxybutyrate intervention.

Data extraction: Seven human studies were included for the quantitative analysis.

Data analysis: Our results showed that ketone therapy significantly improved left ventricular ejection fraction (standardized mean difference, 0.52 [95% CI, 0.25-0.80]; I2 = 0%), cardiac output (0.84 [95% CI, 0.36-1.32]; I2 = 68%) and stroke volume (0.47 [95% CI, 0.10-0.84]; I2 = 39%), and significantly reduced systemic vascular resistance (-0.92 [95% CI, -1.52 to -0.33]; I2 = 74%) without influencing mean arterial pressure (-0.09 [95% CI: -0.40 to 0.22]; I2 = 0%) in patients with HF. Subgroup analysis revealed that the enhanced cardiac function and favorable hemodynamic effects of ketone therapy were also applicable to individuals without HF.

Conclusions: Ketone therapy may significantly improve cardiac systolic function and hemodynamics in patients with HF and in patients without HF, suggesting it may be a promising treatment for patients with HF and also a beneficial medical strategy for patients without HF or healthy individuals.

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引用次数: 0
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-01-28 DOI: 10.1093/nutrit/nuae226
Li Hu, Periyannan Velu, Kousalya Prabahar, Benjamin Hernández-Wolters, Hamed Kord-Varkaneh, Yan Xu

Context: Previous studies have explored the relationship between vitamin D and lipid profile in individuals with obesity or overweight women, but the results have been inconsistent.

Objective: This meta-analysis and systematic review of randomized controlled trials (RCTs) was conducted to assess the effect of vitamin D on lipid profile in women who are overweight or obese.

Data sources: A meticulous search strategy was used across the Scopus, PubMed/Medline, Web of Science, and Embase databases up to June 2024.

Data extraction: RCT studies administering vitamin D to overweight or obese women were extracted. A random-effects model was applied to compute the weighted mean difference (WMD) and 95% CIs of the intervention on each variable.

Data analyses: Thirteen eligible publications with 16 arms focused on low-density-lipoprotein cholesterol (LDL-C), 16 arms on high-density-lipoprotein cholesterol (HDL-C), 18 arms on total cholesterol (TC), and 18 arms on triglycerides (TG) were included in the final quantitative analysis. Vitamin D supplementation resulted in significant reductions in TG (WMD: -6.13 mg/dL; 95% CI: -8.99 to -3.28; P = .000) and TC (WMD: -4.45 mg/dL; 95% CI: -7.06 to -1.83; P = .001), as well as a significant increase in HDL-C concentrations (WMD: 1.54 mg/dL; 95% CI: 0.57 to 2.52; P = .002). Stratified analysis indicated a greater reduction in TG levels in studies with a mean baseline TG concentration ≥150 mg/dL (WMD: -23.58 mg/dL) and when vitamin D was administered for ≤26 weeks (WMD: -11.44 mg/dL).

Conclusion: According to our findings, vitamin D has a significant effect on hypertriglyceridemia in individuals who are overweight or obese. However, vitamin D has no significant effect on LDL-C concentrations in this population.

{"title":"Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.","authors":"Li Hu, Periyannan Velu, Kousalya Prabahar, Benjamin Hernández-Wolters, Hamed Kord-Varkaneh, Yan Xu","doi":"10.1093/nutrit/nuae226","DOIUrl":"https://doi.org/10.1093/nutrit/nuae226","url":null,"abstract":"<p><strong>Context: </strong>Previous studies have explored the relationship between vitamin D and lipid profile in individuals with obesity or overweight women, but the results have been inconsistent.</p><p><strong>Objective: </strong>This meta-analysis and systematic review of randomized controlled trials (RCTs) was conducted to assess the effect of vitamin D on lipid profile in women who are overweight or obese.</p><p><strong>Data sources: </strong>A meticulous search strategy was used across the Scopus, PubMed/Medline, Web of Science, and Embase databases up to June 2024.</p><p><strong>Data extraction: </strong>RCT studies administering vitamin D to overweight or obese women were extracted. A random-effects model was applied to compute the weighted mean difference (WMD) and 95% CIs of the intervention on each variable.</p><p><strong>Data analyses: </strong>Thirteen eligible publications with 16 arms focused on low-density-lipoprotein cholesterol (LDL-C), 16 arms on high-density-lipoprotein cholesterol (HDL-C), 18 arms on total cholesterol (TC), and 18 arms on triglycerides (TG) were included in the final quantitative analysis. Vitamin D supplementation resulted in significant reductions in TG (WMD: -6.13 mg/dL; 95% CI: -8.99 to -3.28; P = .000) and TC (WMD: -4.45 mg/dL; 95% CI: -7.06 to -1.83; P = .001), as well as a significant increase in HDL-C concentrations (WMD: 1.54 mg/dL; 95% CI: 0.57 to 2.52; P = .002). Stratified analysis indicated a greater reduction in TG levels in studies with a mean baseline TG concentration ≥150 mg/dL (WMD: -23.58 mg/dL) and when vitamin D was administered for ≤26 weeks (WMD: -11.44 mg/dL).</p><p><strong>Conclusion: </strong>According to our findings, vitamin D has a significant effect on hypertriglyceridemia in individuals who are overweight or obese. However, vitamin D has no significant effect on LDL-C concentrations in this population.</p>","PeriodicalId":19469,"journal":{"name":"Nutrition reviews","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Food Assistance: A Scoping Review Examining Associations of Nonfood Social Safety Net Programs in the United States With Food Insecurity and Nutrition Outcomes. 超越粮食援助:对美国非食品社会安全网计划与食品不安全和营养结果相关性的范围审查》(A Scoping Review Examining Associations of Nonfood Social Safety Net Programs With Food Insecurity and Nutrition Outcomes.
IF 5.9 2区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2025-01-27 DOI: 10.1093/nutrit/nuae216
Emily W Duffy, Mary Kathryn Poole, David Gonzalez, Joshua Petimar, Eliza W Kinsey, Paul R Shafer, Carrie Baldwin-SoRelle, Anna E Austin

Objective: To conduct a scoping review to summarize the state of the evidence on associations between participation in nonfood social safety net programs (eg, income assistance, housing assistance) in the United States and food- and nutrition insecurity-related outcomes.

Background: Food and nutrition insecurity are persistent public health challenges in the United States that increase chronic disease risk and exacerbate health disparities. Several food assistance programs enhance food and nutrition security. Nonfood social safety net programs, however, may also improve these outcomes by relieving households' financial strain. Understanding the scope of research on nonfood social safety net programs' associations with not only food insecurity but also nutrition insecurity is needed to understand their potential to reduce the burden of diet-related chronic disease.

Methods: Six databases were systematically searched for peer-reviewed articles. Articles were included if they were published between 1995 and 2023; conducted in the United States; available in English; included a dependent variable of food- and/or nutrition insecurity-related measures; and included an independent variable of participation in a federally funded, nonfood social safety net program.

Results: Included articles (n = 65) reported on studies that examined 10 unique social safety net programs; 8 studies examined program interactions. Twenty studies focused on COVID-19 pandemic-era programs. Fifty-eight studies used food insecurity, food insufficiency, or food hardship as outcomes, and 11 studies used nutrition insecurity-related outcomes. Overall, results suggest that participation in nonfood social safety net programs is associated with reductions in food insecurity. Current evidence for an association between program participation and nutrition insecurity-related outcomes is limited.

Conclusion: Further research is warranted on the association between nonfood social safety net programs and nutrition insecurity; potential interactions between social safety net programs; associations between the expiration of pandemic-era programs and food and nutrition insecurity; and how program impacts might differ among populations with persistent disparities in food and nutrition insecurity.

{"title":"Beyond Food Assistance: A Scoping Review Examining Associations of Nonfood Social Safety Net Programs in the United States With Food Insecurity and Nutrition Outcomes.","authors":"Emily W Duffy, Mary Kathryn Poole, David Gonzalez, Joshua Petimar, Eliza W Kinsey, Paul R Shafer, Carrie Baldwin-SoRelle, Anna E Austin","doi":"10.1093/nutrit/nuae216","DOIUrl":"https://doi.org/10.1093/nutrit/nuae216","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a scoping review to summarize the state of the evidence on associations between participation in nonfood social safety net programs (eg, income assistance, housing assistance) in the United States and food- and nutrition insecurity-related outcomes.</p><p><strong>Background: </strong>Food and nutrition insecurity are persistent public health challenges in the United States that increase chronic disease risk and exacerbate health disparities. Several food assistance programs enhance food and nutrition security. Nonfood social safety net programs, however, may also improve these outcomes by relieving households' financial strain. Understanding the scope of research on nonfood social safety net programs' associations with not only food insecurity but also nutrition insecurity is needed to understand their potential to reduce the burden of diet-related chronic disease.</p><p><strong>Methods: </strong>Six databases were systematically searched for peer-reviewed articles. Articles were included if they were published between 1995 and 2023; conducted in the United States; available in English; included a dependent variable of food- and/or nutrition insecurity-related measures; and included an independent variable of participation in a federally funded, nonfood social safety net program.</p><p><strong>Results: </strong>Included articles (n = 65) reported on studies that examined 10 unique social safety net programs; 8 studies examined program interactions. Twenty studies focused on COVID-19 pandemic-era programs. Fifty-eight studies used food insecurity, food insufficiency, or food hardship as outcomes, and 11 studies used nutrition insecurity-related outcomes. Overall, results suggest that participation in nonfood social safety net programs is associated with reductions in food insecurity. Current evidence for an association between program participation and nutrition insecurity-related outcomes is limited.</p><p><strong>Conclusion: </strong>Further research is warranted on the association between nonfood social safety net programs and nutrition insecurity; potential interactions between social safety net programs; associations between the expiration of pandemic-era programs and food and nutrition insecurity; and how program impacts might differ among populations with persistent disparities in food and nutrition insecurity.</p>","PeriodicalId":19469,"journal":{"name":"Nutrition reviews","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Nutrition reviews
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