R Wang, Yf Yu, Wr Yu, Sy Sun, Ym Lei, Yx Li, Cx Lu, Jn Zhai, Fr Bai, Fz Ren, Jq Huang, J Chen
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引用次数: 0
摘要
益生菌、益生元和后益生元可通过其免疫调节作用对与 B 细胞有关的疾病产生重大影响。它们能增强免疫系统的功能,特别是对 B 细胞的影响,B 细胞起源于骨髓,对抗体的产生和免疫记忆至关重要。这些物质通过调节肠道微生物群、加强上皮屏障以及直接与先天性和适应性免疫系统的各种成分相互作用,在控制过敏、自身免疫性疾病和炎症方面具有治疗潜力。这篇综述强调了进一步研究益生菌、益生元和后益生元调节 B 细胞的确切机制的迫切需要。获得这一认识有助于利用这些膳食成分的免疫调节特性,开发出更有效的治疗 B 细胞相关疾病的方法。
Roles of Probiotics, Prebiotics, and Postbiotics in B-cell mediated Immune Regulation.
Probiotics, prebiotics, and postbiotics can significantly influence B-cell-related diseases through their immunomodulatory effects. They enhance the immune system's function, particularly affecting B cells, which originate in the bone marrow and are crucial for antibody production and immune memory. These substances have therapeutic potential in managing allergies, autoimmune diseases, and inflammatory conditions by regulating the gut microbiota, strengthening epithelial barriers, and directly interacting with various components of the innate and adaptive immune systems. The review highlights the critical need for further research into the precise mechanisms through which probiotics, prebiotics, and postbiotics modulate B cells. Gaining this understanding could facilitate the development of more effective treatments for B-cell-related diseases by harnessing the immunomodulatory properties of these dietary components.
期刊介绍:
The Journal of Nutrition (JN/J Nutr) publishes peer-reviewed original research papers covering all aspects of experimental nutrition in humans and other animal species; special articles such as reviews and biographies of prominent nutrition scientists; and issues, opinions, and commentaries on controversial issues in nutrition. Supplements are frequently published to provide extended discussion of topics of special interest.