E. Pouly , A. Biguenet , P. Cholley , D. Hocquet , X. Bertrand
{"title":"法国一家新生儿病房爆发多重耐药溶血葡萄球菌ST29。","authors":"E. Pouly , A. Biguenet , P. Cholley , D. Hocquet , X. Bertrand","doi":"10.1016/j.jhin.2024.11.017","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div><em>Staphylococcus haemolyticus</em> is a clinically relevant coagulase-negative staphylococcus frequently responsible for hospital-acquired infections, especially in premature newborns.</div></div><div><h3>Aim</h3><div>To describe an outbreak of multidrug-resistant <em>S</em>. <em>haemolyticus</em> in a neonatal department.</div></div><div><h3>Methods</h3><div>The outbreak was investigated using classical methods, including screening of the patients, genotyping of the isolates and environmental survey. Numerous infection control measures were implemented.</div></div><div><h3>Findings</h3><div>In 2022 and 2023, a clonal outbreak of multidrug-resistant <em>S. haemolyticus</em> ST29 (40 infections and 71 carriages) occurred in the neonatology department of a University Hospital in France. The infection control measures implemented only partially controlled the outbreak. Although our investigation did not clearly identify the source and mode of transmission, a reservoir constituted by patients and transmission by healthcare workers are the most likely. This episode occurred in a context of countrywide outbreaks of <em>S. haemolyticus</em> ST29 in several French neonatology departments.</div></div><div><h3>Conclusion</h3><div>This prolonged outbreak of <em>S. haemolyticus</em> ST29 accounted for the increase in the incidence of <em>S. haemolyticus</em>-related infections in French neonatology departments. Implementation of proactive measures is crucial to limit the spread of such pathogens in neonatal ICUs.</div></div>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"156 ","pages":"Pages 17-20"},"PeriodicalIF":3.9000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Outbreak of multidrug-resistant Staphylococcus haemolyticus ST29 in a French neonatal unit\",\"authors\":\"E. Pouly , A. Biguenet , P. Cholley , D. Hocquet , X. Bertrand\",\"doi\":\"10.1016/j.jhin.2024.11.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div><em>Staphylococcus haemolyticus</em> is a clinically relevant coagulase-negative staphylococcus frequently responsible for hospital-acquired infections, especially in premature newborns.</div></div><div><h3>Aim</h3><div>To describe an outbreak of multidrug-resistant <em>S</em>. <em>haemolyticus</em> in a neonatal department.</div></div><div><h3>Methods</h3><div>The outbreak was investigated using classical methods, including screening of the patients, genotyping of the isolates and environmental survey. Numerous infection control measures were implemented.</div></div><div><h3>Findings</h3><div>In 2022 and 2023, a clonal outbreak of multidrug-resistant <em>S. haemolyticus</em> ST29 (40 infections and 71 carriages) occurred in the neonatology department of a University Hospital in France. The infection control measures implemented only partially controlled the outbreak. Although our investigation did not clearly identify the source and mode of transmission, a reservoir constituted by patients and transmission by healthcare workers are the most likely. This episode occurred in a context of countrywide outbreaks of <em>S. haemolyticus</em> ST29 in several French neonatology departments.</div></div><div><h3>Conclusion</h3><div>This prolonged outbreak of <em>S. haemolyticus</em> ST29 accounted for the increase in the incidence of <em>S. haemolyticus</em>-related infections in French neonatology departments. Implementation of proactive measures is crucial to limit the spread of such pathogens in neonatal ICUs.</div></div>\",\"PeriodicalId\":54806,\"journal\":{\"name\":\"Journal of Hospital Infection\",\"volume\":\"156 \",\"pages\":\"Pages 17-20\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hospital Infection\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0195670124004006\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hospital Infection","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0195670124004006","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Outbreak of multidrug-resistant Staphylococcus haemolyticus ST29 in a French neonatal unit
Background
Staphylococcus haemolyticus is a clinically relevant coagulase-negative staphylococcus frequently responsible for hospital-acquired infections, especially in premature newborns.
Aim
To describe an outbreak of multidrug-resistant S. haemolyticus in a neonatal department.
Methods
The outbreak was investigated using classical methods, including screening of the patients, genotyping of the isolates and environmental survey. Numerous infection control measures were implemented.
Findings
In 2022 and 2023, a clonal outbreak of multidrug-resistant S. haemolyticus ST29 (40 infections and 71 carriages) occurred in the neonatology department of a University Hospital in France. The infection control measures implemented only partially controlled the outbreak. Although our investigation did not clearly identify the source and mode of transmission, a reservoir constituted by patients and transmission by healthcare workers are the most likely. This episode occurred in a context of countrywide outbreaks of S. haemolyticus ST29 in several French neonatology departments.
Conclusion
This prolonged outbreak of S. haemolyticus ST29 accounted for the increase in the incidence of S. haemolyticus-related infections in French neonatology departments. Implementation of proactive measures is crucial to limit the spread of such pathogens in neonatal ICUs.
期刊介绍：
The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience.
The Journal welcomes submissions that relate to all aspects of infection prevention and control in healthcare settings. This includes submissions that:
provide new insight into the epidemiology, surveillance, or prevention and control of healthcare-associated infections and antimicrobial resistance in healthcare settings;
provide new insight into cleaning, disinfection and decontamination;
provide new insight into the design of healthcare premises;
describe novel aspects of outbreaks of infection;
throw light on techniques for effective antimicrobial stewardship;
describe novel techniques (laboratory-based or point of care) for the detection of infection or antimicrobial resistance in the healthcare setting, particularly if these can be used to facilitate infection prevention and control;
improve understanding of the motivations of safe healthcare behaviour, or describe techniques for achieving behavioural and cultural change;
improve understanding of the use of IT systems in infection surveillance and prevention and control.
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