改进用于隐形眼镜摩擦测试的摆锤式仪器,模拟实际使用条件

IF 1.6 Q4 ENGINEERING, BIOMEDICAL Biosurface and Biotribology Pub Date : 2024-11-27 DOI:10.1049/bsb2.12086
Ryusuke Nakaoka, Hiroko Iwashita, Yuichi Hori, Kiyoshi Mabuchi, Toru Matsunaga, Yuji Haishima, Eiichi Yamamoto
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引用次数: 0

摘要

隐形眼镜(CL)与角膜或结膜表面之间的摩擦被认为是引发CL相关不良反应的关键因素之一。然而,摩擦特性与这些效应之间的关系尚不清楚。传统的测量方法往往不能复制真实的条件,因此强调需要更有效的仪器。在这项研究中,作者开发了一种优化的钟摆装置,与倾斜仪集成,以增强CL摩擦系数的测量,从而提高其精度和与临床环境的相关性。这种新设计允许基于每个振动周期的振幅衰减更快、更容易地计算摩擦系数,超过了以前基于视频的方法的准确性。钟摆的半球组件由乙烯-丙烯-二烯单体橡胶(EPDM) 30制成,其弹性模量与人类眼球相似,创造了一个密切模仿现实世界使用的测量环境。作者通过评估半球刚度和生理盐水体积对摩擦系数的影响来优化装置。作者记录的多个透镜的测量,特别是由narafilcon A制成的透镜A,显示出不同半球材料的显著一致性,最佳盐水体积为150 μL,摩擦系数为0.026±0.003。摩擦系数在透镜底曲线、直径、中心厚度或功率的变化中没有统计学上的显著差异。这种改进的仪器证明了在模拟临床使用条件下有效测量摩擦系数的能力,提供了快速可靠的结果。研究结果验证了该装置,并表明其在评估CL属性方面具有更广泛的应用潜力,从而促进了未来对各种CL的材料特性和安全性的研究,包括装饰镜片。
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Improvement of a pendulum-type apparatus for friction test of a contact lens to simulate the conditions of its actual usage

Friction between the contact lens (CL) and the corneal or conjunctival surfaces is considered one of key factors in triggering CL-associated adverse effects. However, the relationship between friction properties and these effects remains unclear. Traditional measurement methods often fail to replicate real-life conditions, thereby highlighting the need for more effective apparatus. In this study, the authors developed an optimised pendulum apparatus integrated with an inclinometer to enhance the measurement of CL friction coefficients, thereby improving its precision and relevance to clinical settings. This new design allows for faster and easier calculation of the friction coefficient based on the amplitude decay per libration cycle, surpassing the accuracy of previous video-based methods. The pendulum's hemisphere component was made from ethylene–propylene–diene monomer rubber (EPDM) 30, which has an elastic modulus similar to that of a human eyeball, creating a measurement environment that closely mimics real-world usage. The authors optimised the apparatus by evaluating the effects of hemisphere stiffness and saline volume on the friction coefficient. Measurements of multiple lenses recorded by the authors, particularly Lens A, made of narafilcon A, revealed significant consistency across different hemisphere materials with an optimal saline volume of 150 μL yielding a friction coefficient of 0.026 ± 0.003. No statistically significant differences in the friction coefficients were found across variations in the lens base curve, diameter, centre thickness, or power. This improved apparatus demonstrates the capability of effectively measuring friction coefficients under conditions that simulate clinical usage, providing rapid and reliable results. The findings validate the apparatus and suggest its potential for broader applications in assessing CL properties, thereby facilitating future research on the material characteristics and safety of various CLs, including decorative lenses.

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来源期刊
Biosurface and Biotribology
Biosurface and Biotribology Engineering-Mechanical Engineering
CiteScore
1.70
自引率
0.00%
发文量
27
审稿时长
11 weeks
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