{"title":"null不一定是nil:澄清差异检验和等价检验的并行任意性。","authors":"Paul R Hibbing , Gregory J Welk , Philip M Dixon","doi":"10.1016/j.ajcnut.2024.12.017","DOIUrl":null,"url":null,"abstract":"<div><div>In every statistical analysis, a critical step is to determine the smallest effect size of interest, namely, the arbitrary dividing line between meaningful and negligible results. Different tests address this in different ways, and the contrasting approaches can sometimes lead to confusion. We discuss a key example of such confusion, whereby equivalence testing is perceived to be more arbitrary than difference testing. Our comments are intended to clarify that the latter methods share parallel arbitrariness, and to show how the contrary perception is fueled by the habituated use of “nil null hypotheses” in difference testing. The main premise is that nil null hypotheses give an appearance of objectivity by making the smallest effect size of interest an implicit factor in the interpretation stage of difference testing. When contrasted with the requirements of equivalence testing (where the smallest effect size of interest must be explicitly declared and justified a priori, in the form of the equivalence zone), it is therefore understandable how the misperception of greater arbitrariness could emerge. By combating the latter misperception, our comments serve to promote good practice in both difference testing and equivalence testing.</div></div>","PeriodicalId":50813,"journal":{"name":"American Journal of Clinical Nutrition","volume":"121 2","pages":"Pages 207-212"},"PeriodicalIF":6.5000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The null need not be nil: Clarifying the parallel arbitrariness of difference testing and equivalence testing\",\"authors\":\"Paul R Hibbing , Gregory J Welk , Philip M Dixon\",\"doi\":\"10.1016/j.ajcnut.2024.12.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>In every statistical analysis, a critical step is to determine the smallest effect size of interest, namely, the arbitrary dividing line between meaningful and negligible results. Different tests address this in different ways, and the contrasting approaches can sometimes lead to confusion. We discuss a key example of such confusion, whereby equivalence testing is perceived to be more arbitrary than difference testing. Our comments are intended to clarify that the latter methods share parallel arbitrariness, and to show how the contrary perception is fueled by the habituated use of “nil null hypotheses” in difference testing. The main premise is that nil null hypotheses give an appearance of objectivity by making the smallest effect size of interest an implicit factor in the interpretation stage of difference testing. When contrasted with the requirements of equivalence testing (where the smallest effect size of interest must be explicitly declared and justified a priori, in the form of the equivalence zone), it is therefore understandable how the misperception of greater arbitrariness could emerge. By combating the latter misperception, our comments serve to promote good practice in both difference testing and equivalence testing.</div></div>\",\"PeriodicalId\":50813,\"journal\":{\"name\":\"American Journal of Clinical Nutrition\",\"volume\":\"121 2\",\"pages\":\"Pages 207-212\"},\"PeriodicalIF\":6.5000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Clinical Nutrition\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0002916524014710\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Clinical Nutrition","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0002916524014710","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
The null need not be nil: Clarifying the parallel arbitrariness of difference testing and equivalence testing
In every statistical analysis, a critical step is to determine the smallest effect size of interest, namely, the arbitrary dividing line between meaningful and negligible results. Different tests address this in different ways, and the contrasting approaches can sometimes lead to confusion. We discuss a key example of such confusion, whereby equivalence testing is perceived to be more arbitrary than difference testing. Our comments are intended to clarify that the latter methods share parallel arbitrariness, and to show how the contrary perception is fueled by the habituated use of “nil null hypotheses” in difference testing. The main premise is that nil null hypotheses give an appearance of objectivity by making the smallest effect size of interest an implicit factor in the interpretation stage of difference testing. When contrasted with the requirements of equivalence testing (where the smallest effect size of interest must be explicitly declared and justified a priori, in the form of the equivalence zone), it is therefore understandable how the misperception of greater arbitrariness could emerge. By combating the latter misperception, our comments serve to promote good practice in both difference testing and equivalence testing.
期刊介绍:
American Journal of Clinical Nutrition is recognized as the most highly rated peer-reviewed, primary research journal in nutrition and dietetics.It focuses on publishing the latest research on various topics in nutrition, including but not limited to obesity, vitamins and minerals, nutrition and disease, and energy metabolism.
Purpose:
The purpose of AJCN is to:
Publish original research studies relevant to human and clinical nutrition.
Consider well-controlled clinical studies describing scientific mechanisms, efficacy, and safety of dietary interventions in the context of disease prevention or health benefits.
Encourage public health and epidemiologic studies relevant to human nutrition.
Promote innovative investigations of nutritional questions employing epigenetic, genomic, proteomic, and metabolomic approaches.
Include solicited editorials, book reviews, solicited or unsolicited review articles, invited controversy position papers, and letters to the Editor related to prior AJCN articles.
Peer Review Process:
All submitted material with scientific content undergoes peer review by the Editors or their designees before acceptance for publication.