旋转径向注射模式对人体肺部异常的高灵敏度电阻抗断层扫描。

IF 2.3 4区 医学 Q3 BIOPHYSICS Physiological measurement Pub Date : 2025-02-06 DOI:10.1088/1361-6579/ada9c2
Oumaima Bader, Najoua Essoukri Ben Amara, Oliver G Ernst, Olfa Kanoun
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引用次数: 0

摘要

目的:电阻抗断层扫描(EIT)是一种用于肺部成像的无创技术。由于边界电压对内部电导率变化的敏感性较低,EIT的一个重大挑战是重建胸部较深区域的图像。电流注入模式是决定性的,因为它影响电流路径、边界电压及其对组织变化的敏感性。& # xD;方法。本文介绍了一种新的电流注入模式,该模式采用径向放置的电极在旋转的径向模式下进行激励。利用模拟人类胸腔的三维计算模型研究了所提出模式的有效性,复制了其几何形状和组织电学特性。为了检查肺部异常的检测,建立了代表健康和不健康状态的模型,包括三个不同位置的癌症样异常。 ;使用有限元分析(FEA)将新模式与常见模式-相邻,跳过1和相对模式进行比较。比较的重点是肺结节内的电流密度和对异常位置变化的敏感性。& # xD;主要结果。结果表明,与周围组织相比,新模式在异常中获得了最大的电流密度,峰值在离异常最近的电极对附近。具体而言,三个位置的电流密度量级分别为72.73 10^{-9}a.m.、145.24 10^{-9}a.m.和26.43 10^{-9}a.m.。此外,该模式对异常位置变化的敏感性优于普通模式。意义:与普通注射模式相比,这些结果证明了所提出的注射模式在检测肺部异常方面的效率。
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Rotating radial injection pattern for highly sensitive electrical impedance tomography of human lung anomalies.

Objective.Electrical impedance tomography (EIT) is a non-invasive technique used for lung imaging. A significant challenge in EIT is reconstructing images of deeper thoracic regions due to the low sensitivity of boundary voltages to internal conductivity variations. The current injection pattern is decisive as it influences the current path, boundary voltages, and their sensitivity to tissue changes.Approach.This study introduces a novel current injection pattern with radially placed electrodes excited in a rotating radial pattern. The effectiveness of the proposed pattern was investigated using a 3D computational model that mimics the human thorax, replicating its geometry and tissue electrical properties. To examine the detection of lung anomalies, models representing both healthy and unhealthy states, including cancer-like anomalies in three different positions, were developed. The new pattern was compared to common patterns-adjacent, skip 1, and opposite-using finite element analysis. The comparison focused on the current density within lung nodules and the sensitivity to changes in anomaly positions.Main results.Results showed that the new pattern achieved the maximum current density within anomalies compared to surrounding tissues, with peak values near the closest electrode pairs to the anomalies. Specifically, current density magnitudes reached72.73⋅10-9A⋅m,145.24⋅10-9A⋅m, and26.43⋅10-9A⋅mfor the three different positions, respectively. Furthermore, the novel pattern's sensitivity to anomaly position changes surpassed the common patterns.Significance.These results demonstrate the efficiency of the proposed injection pattern in detecting lung anomalies compared to the common injection patterns.

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来源期刊
Physiological measurement
Physiological measurement 生物-工程:生物医学
CiteScore
5.50
自引率
9.40%
发文量
124
审稿时长
3 months
期刊介绍: Physiological Measurement publishes papers about the quantitative assessment and visualization of physiological function in clinical research and practice, with an emphasis on the development of new methods of measurement and their validation. Papers are published on topics including: applied physiology in illness and health electrical bioimpedance, optical and acoustic measurement techniques advanced methods of time series and other data analysis biomedical and clinical engineering in-patient and ambulatory monitoring point-of-care technologies novel clinical measurements of cardiovascular, neurological, and musculoskeletal systems. measurements in molecular, cellular and organ physiology and electrophysiology physiological modeling and simulation novel biomedical sensors, instruments, devices and systems measurement standards and guidelines.
期刊最新文献
A low-cost PPG sensor-based empirical study on healthy aging based on changes in PPG morphology. A two-branch framework for blood pressure estimation using photoplethysmography signals with deep learning and clinical prior physiological knowledge. Automated system for diagnosing pulmonary fibrosis using crackle analysis in recorded lung sounds based on iterative envelope mean fractal dimension filter. Rotating radial injection pattern for highly sensitive electrical impedance tomography of human lung anomalies. One-week test-retest stability of heart rate variability during rest and deep breathing.
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