Oumaima Bader, Najoua Essoukri Ben Amara, Oliver G Ernst, Olfa Kanoun
{"title":"旋转径向注射模式对人体肺部异常的高灵敏度电阻抗断层扫描。","authors":"Oumaima Bader, Najoua Essoukri Ben Amara, Oliver G Ernst, Olfa Kanoun","doi":"10.1088/1361-6579/ada9c2","DOIUrl":null,"url":null,"abstract":"<p><p><i>Objective.</i>Electrical impedance tomography (EIT) is a non-invasive technique used for lung imaging. A significant challenge in EIT is reconstructing images of deeper thoracic regions due to the low sensitivity of boundary voltages to internal conductivity variations. The current injection pattern is decisive as it influences the current path, boundary voltages, and their sensitivity to tissue changes.<i>Approach.</i>This study introduces a novel current injection pattern with radially placed electrodes excited in a rotating radial pattern. The effectiveness of the proposed pattern was investigated using a 3D computational model that mimics the human thorax, replicating its geometry and tissue electrical properties. To examine the detection of lung anomalies, models representing both healthy and unhealthy states, including cancer-like anomalies in three different positions, were developed. The new pattern was compared to common patterns-adjacent, skip 1, and opposite-using finite element analysis. The comparison focused on the current density within lung nodules and the sensitivity to changes in anomaly positions.<i>Main results.</i>Results showed that the new pattern achieved the maximum current density within anomalies compared to surrounding tissues, with peak values near the closest electrode pairs to the anomalies. Specifically, current density magnitudes reached72.73⋅10-9A⋅m,145.24⋅10-9A⋅m, and26.43⋅10-9A⋅mfor the three different positions, respectively. Furthermore, the novel pattern's sensitivity to anomaly position changes surpassed the common patterns.<i>Significance.</i>These results demonstrate the efficiency of the proposed injection pattern in detecting lung anomalies compared to the common injection patterns.</p>","PeriodicalId":20047,"journal":{"name":"Physiological measurement","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rotating radial injection pattern for highly sensitive electrical impedance tomography of human lung anomalies.\",\"authors\":\"Oumaima Bader, Najoua Essoukri Ben Amara, Oliver G Ernst, Olfa Kanoun\",\"doi\":\"10.1088/1361-6579/ada9c2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Objective.</i>Electrical impedance tomography (EIT) is a non-invasive technique used for lung imaging. A significant challenge in EIT is reconstructing images of deeper thoracic regions due to the low sensitivity of boundary voltages to internal conductivity variations. The current injection pattern is decisive as it influences the current path, boundary voltages, and their sensitivity to tissue changes.<i>Approach.</i>This study introduces a novel current injection pattern with radially placed electrodes excited in a rotating radial pattern. The effectiveness of the proposed pattern was investigated using a 3D computational model that mimics the human thorax, replicating its geometry and tissue electrical properties. To examine the detection of lung anomalies, models representing both healthy and unhealthy states, including cancer-like anomalies in three different positions, were developed. The new pattern was compared to common patterns-adjacent, skip 1, and opposite-using finite element analysis. The comparison focused on the current density within lung nodules and the sensitivity to changes in anomaly positions.<i>Main results.</i>Results showed that the new pattern achieved the maximum current density within anomalies compared to surrounding tissues, with peak values near the closest electrode pairs to the anomalies. Specifically, current density magnitudes reached72.73⋅10-9A⋅m,145.24⋅10-9A⋅m, and26.43⋅10-9A⋅mfor the three different positions, respectively. Furthermore, the novel pattern's sensitivity to anomaly position changes surpassed the common patterns.<i>Significance.</i>These results demonstrate the efficiency of the proposed injection pattern in detecting lung anomalies compared to the common injection patterns.</p>\",\"PeriodicalId\":20047,\"journal\":{\"name\":\"Physiological measurement\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-02-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiological measurement\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1088/1361-6579/ada9c2\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiological measurement","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1088/1361-6579/ada9c2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
Rotating radial injection pattern for highly sensitive electrical impedance tomography of human lung anomalies.
Objective.Electrical impedance tomography (EIT) is a non-invasive technique used for lung imaging. A significant challenge in EIT is reconstructing images of deeper thoracic regions due to the low sensitivity of boundary voltages to internal conductivity variations. The current injection pattern is decisive as it influences the current path, boundary voltages, and their sensitivity to tissue changes.Approach.This study introduces a novel current injection pattern with radially placed electrodes excited in a rotating radial pattern. The effectiveness of the proposed pattern was investigated using a 3D computational model that mimics the human thorax, replicating its geometry and tissue electrical properties. To examine the detection of lung anomalies, models representing both healthy and unhealthy states, including cancer-like anomalies in three different positions, were developed. The new pattern was compared to common patterns-adjacent, skip 1, and opposite-using finite element analysis. The comparison focused on the current density within lung nodules and the sensitivity to changes in anomaly positions.Main results.Results showed that the new pattern achieved the maximum current density within anomalies compared to surrounding tissues, with peak values near the closest electrode pairs to the anomalies. Specifically, current density magnitudes reached72.73⋅10-9A⋅m,145.24⋅10-9A⋅m, and26.43⋅10-9A⋅mfor the three different positions, respectively. Furthermore, the novel pattern's sensitivity to anomaly position changes surpassed the common patterns.Significance.These results demonstrate the efficiency of the proposed injection pattern in detecting lung anomalies compared to the common injection patterns.
期刊介绍:
Physiological Measurement publishes papers about the quantitative assessment and visualization of physiological function in clinical research and practice, with an emphasis on the development of new methods of measurement and their validation.
Papers are published on topics including:
applied physiology in illness and health
electrical bioimpedance, optical and acoustic measurement techniques
advanced methods of time series and other data analysis
biomedical and clinical engineering
in-patient and ambulatory monitoring
point-of-care technologies
novel clinical measurements of cardiovascular, neurological, and musculoskeletal systems.
measurements in molecular, cellular and organ physiology and electrophysiology
physiological modeling and simulation
novel biomedical sensors, instruments, devices and systems
measurement standards and guidelines.