IF 4 3区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY Biodata Mining Pub Date : 2025-01-30 DOI:10.1186/s13040-025-00425-0
Getnet Bogale Begashaw, Temesgen Zewotir, Haile Mekonnen Fenta
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引用次数: 0

摘要

背景:本研究采用 LSTM-FC 神经网络来解决埃塞俄比亚儿童营养不良这一关键的公共卫生问题。通过采用这种方法,研究旨在对儿童的营养状况进行分类,并预测不同营养不良状态随时间的变化。这项分析基于从 "年轻生命 "队列研究中提取的纵向数据,该研究在 2002 年至 2016 年的五轮调查中对 1,997 名埃塞俄比亚儿童进行了跟踪调查。本文采用了严格的数据预处理,包括处理缺失值、归一化和平衡,以确保模型的最佳性能。使用 SHapley Additive exPlanations 进行了特征选择,以确定影响营养状况预测的关键因素。在模型训练过程中对超参数进行了全面调整,以优化性能。此外,本文还比较了 LSTM-FC 与现有基线模型的性能,以证明其优越性。我们在配备 GPU 的系统上使用 Python 的 TensorFlow 和 Keras 库进行模型训练:结果:与评估儿童营养状况的基线模型相比,LSTM-FC 的预测准确性和长期预测能力更胜一筹。该模型的分类和预测准确率超过 93%,对正常(N)和发育迟缓与消瘦(SW)类别的预测完全准确,对大多数其他营养状况的预测误差极小,在少数情况下略有高估或低估。LSTM-FC 模型在多个褶皱中表现出很强的泛化性能,具有很高的召回率和一致的 F1 分数,这表明它在预测营养状况方面具有很强的鲁棒性。我们分析了儿童从青春晚期向成年早期过渡期间营养状况的普遍性。结果显示,男性正常营养状况明显下降,从 5 岁时的 58.3% 降至 25 岁时的 33.5%。与此同时,严重营养不良(包括体重不足、发育迟缓和消瘦(USW))的风险从 1.3% 上升到 9.4%:结论:在对埃塞俄比亚儿童营养状况进行分类和预测方面,LSTM-FC 模型优于基准方法。研究结果揭示了营养不良状况急剧上升的趋势,强调了采取紧急公共卫生干预措施的必要性。
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A deep learning approach for classifying and predicting children's nutritional status in Ethiopia using LSTM-FC neural networks.

Background: This study employs a LSTM-FC neural networks to address the critical public health issue of child undernutrition in Ethiopia. By employing this method, the study aims classify children's nutritional status and predict transitions between different undernutrition states over time. This analysis is based on longitudinal data extracted from the Young Lives cohort study, which tracked 1,997 Ethiopian children across five survey rounds conducted from 2002 to 2016. This paper applies rigorous data preprocessing, including handling missing values, normalization, and balancing, to ensure optimal model performance. Feature selection was performed using SHapley Additive exPlanations to identify key factors influencing nutritional status predictions. Hyperparameter tuning was thoroughly applied during model training to optimize performance. Furthermore, this paper compares the performance of LSTM-FC with existing baseline models to demonstrate its superiority. We used Python's TensorFlow and Keras libraries on a GPU-equipped system for model training.

Results: LSTM-FC demonstrated superior predictive accuracy and long-term forecasting compared to baseline models for assessing child nutritional status. The classification and prediction performance of the model showed high accuracy rates above 93%, with perfect predictions for Normal (N) and Stunted & Wasted (SW) categories, minimal errors in most other nutritional statuses, and slight over- or underestimations in a few instances. The LSTM-FC model demonstrates strong generalization performance across multiple folds, with high recall and consistent F1-scores, indicating its robustness in predicting nutritional status. We analyzed the prevalence of children's nutritional status during their transition from late adolescence to early adulthood. The results show a notable decline in normal nutritional status among males, decreasing from 58.3% at age 5 to 33.5% by age 25. At the same time, the risk of severe undernutrition, including conditions of being underweight, stunted, and wasted (USW), increased from 1.3% to 9.4%.

Conclusions: The LSTM-FC model outperforms baseline methods in classifying and predicting Ethiopian children's nutritional statuses. The findings reveal a critical rise in undernutrition, emphasizing the need for urgent public health interventions.

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来源期刊
Biodata Mining
Biodata Mining MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
7.90
自引率
0.00%
发文量
28
审稿时长
23 weeks
期刊介绍: BioData Mining is an open access, open peer-reviewed journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects of knowledge discovery from large-scale genetic, transcriptomic, genomic, proteomic, and metabolomic data. Topical areas include, but are not limited to: -Development, evaluation, and application of novel data mining and machine learning algorithms. -Adaptation, evaluation, and application of traditional data mining and machine learning algorithms. -Open-source software for the application of data mining and machine learning algorithms. -Design, development and integration of databases, software and web services for the storage, management, retrieval, and analysis of data from large scale studies. -Pre-processing, post-processing, modeling, and interpretation of data mining and machine learning results for biological interpretation and knowledge discovery.
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