Muhammad Zahid Sarfaraz , Sidra Abbas , Muhammad Arfan Zaman , Asia Parveen , Safina Kousar , Muhammad Zulqarnain
{"title":"A step forward to revolutionize the eimeriosis controlling strategies in cattle by using traditional medication","authors":"Muhammad Zahid Sarfaraz , Sidra Abbas , Muhammad Arfan Zaman , Asia Parveen , Safina Kousar , Muhammad Zulqarnain","doi":"10.1016/j.exppara.2025.108926","DOIUrl":null,"url":null,"abstract":"<div><div>More than 10 species of <em>Eimeria</em> is found in cattle but <em>Eimeria zuernii</em> is one of the most pathogenic protozoan parasites affecting the global livestock industry. At the herd level, <em>E. zuernii</em> can cause illness in 10–80% of animals and reduce gross margins by 8–9%, leading to estimated annual losses of $731 million. This review highlights the economic impact, prevalence, and current control methods for <em>E. zuernii</em> infections, as well as the challenges associated with treatment and the development of alternative control methods. In the past two decades, 22 studies have examined synthetic drugs for managing eimeriosis in cattle. Various anticoccidial drugs (AcDs; Amprolium, decoquinate, ionophores, monensin, lasalocid, toltrazuril etc) have been used, but the efficacy of these drugs is no more consistent. Because of this, <em>E. zuernii</em> develops resistance to some of these anticoccidials. This trend highlights the urgent need for alternative treatments. The medicinal plants being enriched with various phytochemicals like flavonoids, tannins, alkaloids, terpenes etc have been reported as potential anticoccidial, anthelmintic and antimicrobial efficacy against the different parasites including <em>Eimeria</em> species in chicken, pig and rabbits. However, this review suggests the research community to treat the <em>E. zuernii</em> with a plant based medication (oils and extracts). This review critically emphasizes the need to acknowledge the significant role of medicinal plants in controlling eimeriosis and also the large-scale trials or standardization of plant-based therapies is required. By incorporating plant-based remedies into integrated treatment strategies alongside synthetic drugs and improved sanitation practices, we can effectively minimize financial losses and safeguard livestock health.</div></div>","PeriodicalId":12117,"journal":{"name":"Experimental parasitology","volume":"271 ","pages":"Article 108926"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental parasitology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014489425000311","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PARASITOLOGY","Score":null,"Total":0}
A step forward to revolutionize the eimeriosis controlling strategies in cattle by using traditional medication
More than 10 species of Eimeria is found in cattle but Eimeria zuernii is one of the most pathogenic protozoan parasites affecting the global livestock industry. At the herd level, E. zuernii can cause illness in 10–80% of animals and reduce gross margins by 8–9%, leading to estimated annual losses of $731 million. This review highlights the economic impact, prevalence, and current control methods for E. zuernii infections, as well as the challenges associated with treatment and the development of alternative control methods. In the past two decades, 22 studies have examined synthetic drugs for managing eimeriosis in cattle. Various anticoccidial drugs (AcDs; Amprolium, decoquinate, ionophores, monensin, lasalocid, toltrazuril etc) have been used, but the efficacy of these drugs is no more consistent. Because of this, E. zuernii develops resistance to some of these anticoccidials. This trend highlights the urgent need for alternative treatments. The medicinal plants being enriched with various phytochemicals like flavonoids, tannins, alkaloids, terpenes etc have been reported as potential anticoccidial, anthelmintic and antimicrobial efficacy against the different parasites including Eimeria species in chicken, pig and rabbits. However, this review suggests the research community to treat the E. zuernii with a plant based medication (oils and extracts). This review critically emphasizes the need to acknowledge the significant role of medicinal plants in controlling eimeriosis and also the large-scale trials or standardization of plant-based therapies is required. By incorporating plant-based remedies into integrated treatment strategies alongside synthetic drugs and improved sanitation practices, we can effectively minimize financial losses and safeguard livestock health.
期刊介绍:
Experimental Parasitology emphasizes modern approaches to parasitology, including molecular biology and immunology. The journal features original research papers on the physiological, metabolic, immunologic, biochemical, nutritional, and chemotherapeutic aspects of parasites and host-parasite relationships.