IF 1.4 4区 医学 Q3 PARASITOLOGY Experimental parasitology Pub Date : 2025-03-04 DOI:10.1016/j.exppara.2025.108926
Muhammad Zahid Sarfaraz , Sidra Abbas , Muhammad Arfan Zaman , Asia Parveen , Safina Kousar , Muhammad Zulqarnain
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摘要

牛体内有 10 多种艾美耳菌,但祖牛艾美耳菌是影响全球畜牧业的致病性最强的原生动物寄生虫之一。在牛群中,祖牛艾美拉虫可导致 10% 到 80% 的动物患病,并使毛利率降低 8-9%,估计每年造成 7.31 亿美元的损失。本综述强调了猪圆环病毒感染的经济影响、流行情况和当前的控制方法,以及与治疗和开发替代控制方法相关的挑战。在过去 20 年中,有 22 项研究探讨了控制牛埃默里病的合成药物。各种抗球虫药物(AcDs;Amprolium、decoquinate、ionophores、monensin、lasalocid、toltrazuril 等)已被使用,但这些药物的疗效并不一致。因此,E. zuernii 对其中一些抗球虫药产生了抗药性。这一趋势凸显了对替代疗法的迫切需求。据报道,富含黄酮类、单宁酸、生物碱、萜类等各种植物化学物质的药用植物对鸡、猪和兔的不同寄生虫(包括艾美耳菌)具有潜在的抗球虫、驱虫和抗菌功效。不过,本综述建议研究界使用植物性药物(油和提取物)治疗艾美耳病。这篇综述批判性地强调了承认药用植物在控制埃默里病中的重要作用的必要性,以及对植物疗法进行大规模试验或标准化的必要性。通过将植物疗法纳入综合治疗策略,与合成药物和改进的卫生习惯一起使用,我们可以有效地减少经济损失,保障牲畜健康。
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A step forward to revolutionize the eimeriosis controlling strategies in cattle by using traditional medication
More than 10 species of Eimeria is found in cattle but Eimeria zuernii is one of the most pathogenic protozoan parasites affecting the global livestock industry. At the herd level, E. zuernii can cause illness in 10–80% of animals and reduce gross margins by 8–9%, leading to estimated annual losses of $731 million. This review highlights the economic impact, prevalence, and current control methods for E. zuernii infections, as well as the challenges associated with treatment and the development of alternative control methods. In the past two decades, 22 studies have examined synthetic drugs for managing eimeriosis in cattle. Various anticoccidial drugs (AcDs; Amprolium, decoquinate, ionophores, monensin, lasalocid, toltrazuril etc) have been used, but the efficacy of these drugs is no more consistent. Because of this, E. zuernii develops resistance to some of these anticoccidials. This trend highlights the urgent need for alternative treatments. The medicinal plants being enriched with various phytochemicals like flavonoids, tannins, alkaloids, terpenes etc have been reported as potential anticoccidial, anthelmintic and antimicrobial efficacy against the different parasites including Eimeria species in chicken, pig and rabbits. However, this review suggests the research community to treat the E. zuernii with a plant based medication (oils and extracts). This review critically emphasizes the need to acknowledge the significant role of medicinal plants in controlling eimeriosis and also the large-scale trials or standardization of plant-based therapies is required. By incorporating plant-based remedies into integrated treatment strategies alongside synthetic drugs and improved sanitation practices, we can effectively minimize financial losses and safeguard livestock health.
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来源期刊
Experimental parasitology
Experimental parasitology 医学-寄生虫学
CiteScore
3.10
自引率
4.80%
发文量
160
审稿时长
3 months
期刊介绍: Experimental Parasitology emphasizes modern approaches to parasitology, including molecular biology and immunology. The journal features original research papers on the physiological, metabolic, immunologic, biochemical, nutritional, and chemotherapeutic aspects of parasites and host-parasite relationships.
期刊最新文献
Editorial Board Evaluation of the resistance of Anisakis spp. larvae to products regularly used in the industry and households Suppression of 8-oxoguanine DNA glycosylase (OGG1) activity produced positive impacts on disease severity, survival, and histopathological features of mice infected with Plasmodium berghei Involvement of Toxoplasma gondii natural antisense transcripts in cellular stress responses Development of a multiplex PCR assay targeting mitochondrial cytochrome oxidase subunit III (cox3) gene for simultaneous specific and sensitive detection of Babesia gibsoni and Babesia vogeli in dogs
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