接触伏马菌素B1污染饲料的猪的现场观察。

Veterinary and human toxicology Pub Date : 2004-12-01
Marco De Liguoro, Claudio Petterino, Giorgia Mezzalira, Sandro Tenti, Licia Ravarotto
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引用次数: 0

摘要

在饲养的最后5个月,对14头猪饲喂福马菌素B1天然污染的饲料,对其血液学和生化效果进行了评价。屠宰后对肝脏和1个肾脏进行组织病理学检查;另一侧肾脏HPLC检测伏马菌素B1残留量。在饲料污染为2和22 mg伏马菌素B1/kg的情况下,第一次采血前计算的伏马菌素B1日摄入量约为50微克/公斤体重,第二次采血和屠宰前计算的伏马菌素日摄入量约为500微克/公斤体重。未观察到血液学变化,但发现对肝功能(ALT和胆固醇)和肝细胞完整性有中度不良影响。肾脏未检测到组织病理学改变,也未检测到伏马菌素残留(LOD 5微克/千克)。污染水平对猪的健康有轻微的影响,但可以观察到。经证实,没有伏马菌素B1携带到食用猪组织中,在研究条件下,预计猪肉产品不会给消费者带来风险。
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Field observations in pigs exposed to fumonisin B1 contaminated feed.

Fourteen pigs, fed during the last 5 mo of rearing on fumonisin B1 naturally contaminated feed, were evaluated for hematological and biochemical effects. After slaughtering of the animals, the liver and 1 kidney underwent histopathological examination; the other kidney was tested by HPLC for fumonisin B1 residues. With feed contamination of 2 and 22 mg fumonisin B1/kg, the calculated daily intake of fumonisin B1 was approximately 50 microg/kg bw before the first blood sampling and approximately 500 microg/kg bw before the second blood sampling and slaughter. No hematological changes were observed, while moderate adverse effects on liver function (ALT and cholesterol) and hepatocyte integritywere found. No histopathological alterations nor fumonisin residues were detected (LOD 5 microg/kg) in the kidneys. The levels of contamination had slight but observed effects on swine health. The lack of fumonisin B1 carry-over to edible swine tissues was confirmed and under the studied conditions, no consumer risk from the pork products was expected.

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