DNA序列的压缩模式匹配。

Lei Chen, Shiyong Lu, Jeffrey Ram
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引用次数: 0

摘要

提出了一种新的DNA序列压缩模式匹配算法——导数Boyer-Moore (d-BM)算法。该算法基于Boyer-Moore方法,这是最流行的字符串匹配算法之一。在这种方法中,我们通过使用两个比特来表示每个A, T, C, G字符来压缩DNA序列和模式。实验表明,该压缩模式匹配算法搜索长DNA模式(长度> 50)的速度比软件包Agrep精确匹配例程快10倍以上,后者被称为最快的模式匹配工具。此外,用这种方法压缩DNA序列可以保证节省75%的空间。在某种程度上,算法速度的提高是由于将字母表大小从4增加到256而提高了Boyer-Moore方法的效率。
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Compressed pattern matching in DNA sequences.

We propose derivative Boyer-Moore (d-BM), a new compressed pattern matching algorithm in DNA sequences. This algorithm is based on the Boyer-Moore method, which is one of the most popular string matching algorithms. In this approach, we compress both DNA sequences and patterns by using two bits to represent each A, T, C, G character. Experiments indicate that this compressed pattern matching algorithm searches long DNA patterns (length > 50) more than 10 times faster than the exact match routine of the software package Agrep, which is known as the fastest pattern matching tool. Moreover, compression of DNA sequences by this method gives a guaranteed space saving of 75%. In part the enhanced speed of the algorithm is due to the increased efficiency of the Boyer-Moore method resulting from an increase in alphabet size from 4 to 256.

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