{"title":"用于个性化生物应用的功能改性高岭土纳米管","authors":"Juan Liao , Hao Wang , Nian Liu , Huaming Yang","doi":"10.1016/j.cis.2022.102812","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Halloysite nanotubes (HNTs) are naturally </span>aluminosilicate clay minerals that have the benefits of large surface areas, high </span>mechanical properties, easy functionalization, and high biocompatibility, HNTs have been developed as multifunctional nanoplatforms for various bioapplications. Although some reviews have summarized the properties and bioapplications of HNTs, it remains unclear how to functionalize the modifications of HNTs for their personalized bioapplications. In this review, based on the physicochemical properties of HNTs, we summarized the methods of functionalized modifications (surface modification and structure modification) on HNTs. Also, we highlighted their personalized bioapplications (anti-bacterial, anti-inflammatory, wound healing, cancer theranostics, bone regenerative, and biosensing) by stressing on the main roles of HNTs. Finally, we provide perspectives on the future of functionalized modifications of HNTs for docking specific biological applications.</p></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":null,"pages":null},"PeriodicalIF":15.9000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":"{\"title\":\"Functionally modified halloysite nanotubes for personalized bioapplications\",\"authors\":\"Juan Liao , Hao Wang , Nian Liu , Huaming Yang\",\"doi\":\"10.1016/j.cis.2022.102812\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Halloysite nanotubes (HNTs) are naturally </span>aluminosilicate clay minerals that have the benefits of large surface areas, high </span>mechanical properties, easy functionalization, and high biocompatibility, HNTs have been developed as multifunctional nanoplatforms for various bioapplications. Although some reviews have summarized the properties and bioapplications of HNTs, it remains unclear how to functionalize the modifications of HNTs for their personalized bioapplications. In this review, based on the physicochemical properties of HNTs, we summarized the methods of functionalized modifications (surface modification and structure modification) on HNTs. Also, we highlighted their personalized bioapplications (anti-bacterial, anti-inflammatory, wound healing, cancer theranostics, bone regenerative, and biosensing) by stressing on the main roles of HNTs. Finally, we provide perspectives on the future of functionalized modifications of HNTs for docking specific biological applications.</p></div>\",\"PeriodicalId\":239,\"journal\":{\"name\":\"Advances in Colloid and Interface Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":15.9000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Colloid and Interface Science\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0001868622002147\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Colloid and Interface Science","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0001868622002147","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Functionally modified halloysite nanotubes for personalized bioapplications
Halloysite nanotubes (HNTs) are naturally aluminosilicate clay minerals that have the benefits of large surface areas, high mechanical properties, easy functionalization, and high biocompatibility, HNTs have been developed as multifunctional nanoplatforms for various bioapplications. Although some reviews have summarized the properties and bioapplications of HNTs, it remains unclear how to functionalize the modifications of HNTs for their personalized bioapplications. In this review, based on the physicochemical properties of HNTs, we summarized the methods of functionalized modifications (surface modification and structure modification) on HNTs. Also, we highlighted their personalized bioapplications (anti-bacterial, anti-inflammatory, wound healing, cancer theranostics, bone regenerative, and biosensing) by stressing on the main roles of HNTs. Finally, we provide perspectives on the future of functionalized modifications of HNTs for docking specific biological applications.
期刊介绍：
"Advances in Colloid and Interface Science" is an international journal that focuses on experimental and theoretical developments in interfacial and colloidal phenomena. The journal covers a wide range of disciplines including biology, chemistry, physics, and technology.
The journal accepts review articles on any topic within the scope of colloid and interface science. These articles should provide an in-depth analysis of the subject matter, offering a critical review of the current state of the field. The author's informed opinion on the topic should also be included. The manuscript should compare and contrast ideas found in the reviewed literature and address the limitations of these ideas.
Typically, the articles published in this journal are written by recognized experts in the field.
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