滨州市不同阶段麻疹防控效果分析

中国疫苗和免疫 Pub Date : 2009-10-01
Guo-Qiang Cao, Ying Yang, Zhi-Guang Zhang
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引用次数: 0

摘要

目的:评价山东省滨州市不同阶段麻疹防控效果。方法:对1956 - 2008年麻疹发病率、麻疹疫苗接种率、人群麻疹IgG抗体免疫水平及控制麻疹的成本效益进行分析。结果:随着麻疹控制策略的实施,麻疹发病率不断下降。麻疹疫苗接种率一直保持在87.12% ~ 93.45%的水平,麻疹IgG抗体的人群免疫水平一直保持在较高水平。根据麻疹免疫战略的进展情况,麻疹控制过程可分为A阶段(1956-1966年,未开展特异性免疫)、B阶段(1967-1978年,麻疹开始普及)、C阶段(1979-1997年,实施扩大免疫计划)和D阶段(1998-2008年,加快麻疹控制和消除)。B期与A期、C期与B期、D期与C期比较,年平均病例数分别减少9989例、18500例和378例,年平均死亡病例数分别减少267例、49例和50例。1967 - 2008年共41年控制和消除麻疹的成本效益比为1:22.97。结论:在滨州市麻疹控制过程中取得了一定效果。应作出更多努力,以实现消除麻疹的目标。
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[Effect of measles control at different stages in Binzhou Municipal].

Objective: To evaluate the effect of measles control at different stages in Binzhou of Shandong.

Methods: The data of measles incidence, measles vaccine (MV) coverage, the population immune levels of measles IgG antibody from 1956 to 2008, and the cost-benefit of measles control were analyzed.

Results: The measles incidences were declined continually with implementing the strategies of measles control. Measles vaccine coverages have been keeping at the level of 87.12%-93.45% and the population immune levels of measles IgG antibody have been remaining at high level after implemention EPI. According to the progress of MV immunization strategy, the process of measles control could be divided into stage A (1956-1966, no specific immunization conducted), stage B (1967-1978, MV began to popularized), stage C (1979-1997, the EPI was implemented) and stage D (1998-2008, accelerated measles control and elimination). To compared between stage B and stage A, stage C and stage B, stage D and stage C, the average annual cases were decreased 9989, 18 500, and 378 respectirely, and the average annual dead cases were reduced 267, 49 and 50 respectively. The cost-benefit ratio was 1:22.97 for total 41 years on the process of the measles control and elimination from 1967 to 2008.

Conclusion: The effect was obtained on the process of measles control in Binzhou city. More efforts should be made to reach the target of measles elimination.

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