[母婴风疹抗体的变化]。

中国疫苗和免疫 Pub Date : 2009-10-01
Rui Ma, Guo-Zhang Xu, Chao Ma
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引用次数: 0

摘要

目的:了解母婴对比抗体水平及婴幼儿风疹变化,为控制先天性风疹综合征提供科学依据。方法:选取浙江省宁波市、黑龙江省哈尔滨市和山东省济南市常住的新生儿、3、6、8、9月龄未患风疹的婴儿及其母亲为研究对象。采用ELISA法检测血清样本。结果:新生儿3、6、8、9的风疹抗体阳性率分别为74.4、14.9、3.3、4.6、15.0%,GMC分别为34.06、5.42、1.48、1.10、1.83IU/ml。母亲风疹抗体阳性率为71.1%,GMC为30.96IU/ml。母婴间相关系数为0.658。结论:母源性风疹抗体随着婴儿的生长而降低。6个月和8个月麻疹抗体阳性率很低,几乎没有保护作用。
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[Change of rubella antibody transferred by mother in infants].

Objective: To Know the antibody level of comparison in maternal-infant pairs and the change of rubella in infants, and to provide scientific basis for controlling congenital rubella syndrome.

Methods: Newborn, 3, 6, 8, 9-month infant who never had rubella and their mothers were residents in Ningbo of Zhejiang, Harbin of Heilongjiang and Jinan of Shandong were collected as objects. Their serum samples were tested by the method of ELISA.

Results: The positive rate of Rubella antibody in newborns, 3, 6, 8, 9, were 74.4, 14.9, 3.3, 4.6, 15.0 percent respectively, and GMC were 34.06, 5.42, 1.48, 1.10, 1.83IU/ml respectively. The positive rate and GMC of Rubella antibody in mothers were 71.1 percent and 30.96IU/ml. The correlation coefficient between mother and infant was 0.658.

Conclusion: Maternal-transferred rubella antibody decreased as the growth of infants. The positive rate of measles antibody was very low in 6 and 8-month, which almost had no protection.

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