[Clinical trial on safety of inactivated split influenza virus vaccine, Anflu in 2007-2008].

Objective: To review the safety of the inactivated split influenza vaccine, Anflu in a large scale population.

Methods: Selecting 14 districts national wide to inject the inactivated split influenza vaccines according schedules among infants, children, youths, adults and elder respectively. All volunteers were observed for AEFI after 7 days vaccinated.

Results: A total of 2794 volunteers aged 6 months to 90 years were enrolled in trials. The overall rate of adverse events was 6.6%.most adverse was mild reaction. Severe, infrequent or new adverse events were not reported. The rate of local reactions was 2.1%. The rate of local pain was 1.7%. The rate of systematic adverse events was 5.0%, fever took up 3.8%.

Conclusion: The inactivated split influenza vaccine, Anflu was safe.