乙型肝炎病毒标志物面板的建立

中国疫苗和免疫 Pub Date : 2009-10-01
Yong Zhang, Feng Wang, Jing-Chen Ma
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引用次数: 0

摘要

目的:建立HBV标志物组。方法:选取155例血浆标本,采用雅培公司MEIA试剂盒检测5种HBV标志物,每例检测2次。任何有2个阳性或阴性结果的血浆都被纳入HBV标记物小组,其他的被排除在外。结果:153例血浆被纳入HBsAg组,154例血浆被纳入抗hbs、抗hbc和抗hbe组。由于只有4例阳性,未建立HBeAg小组。结论:采用高精度试剂盒对足够多的血浆标本进行多次筛选,可建立HBV标志物组。面板应在有限的延伸范围内使用,以避免不必要的错误。
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[Establishment of hepatitis B virus marker panels].

Objective: To establish HBV marker panels.

Methods: 155 blood plasma specimens were selected and each was detected twice for 5 HBV markers with MEIA kits made by Abbott. Any plasma that had 2 positive or negative results were enrolled in the HBV marker panels and others were excluded.

Results: 153 plasma were enrolled in the HBsAg panel and 154 were enrolled in anti-HBs, anti-HBc and anti-HBe panels respectively. Panel of HBeAg was not established because that there were only 4 positives.

Conclusion: HBV marker panels can be established by screening enough blood plasma specimens with high accurate kits for more than one time. The panels should be used in a limited extension to avoid unnecessary mistakes.

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