J E Dumont, X De Deken, F Miot, V Corvilain, B Contempré, R Goyens, C Massart, J Van Sande, A Allaoui, A Botteaux
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H2O2, signal, substrate, mutagen and chemorepellent from physiology to biochemistry and disease.
The history of the study by our group of the generation, the role and the effects of H2O2 in the thyroid, is summarized. The relations with thyroid diseases are discussed: myxedematous cretinism, thyroiditis, thyroid cancer, congenital hypothyroiddism, are discussed. A new role of H2O2 in the chemorepulsion of bacteria is proposed.