矿区金属污染土壤引起大鼠体内金属积累和生物反应。

IF 0.4 4区农林科学 Q4 VETERINARY SCIENCES Japanese Journal of Veterinary Research Pub Date : 2013-02-01

Shouta M M Nakayama, Yoshinori Ikenaka, Kaampwe Muzandu, Kennedy Choongo, John Yabe, Takashi Umemura, Mayumi Ishizuka

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引用次数: 0

摘要

为了评估金属污染对野生动物的影响，我们从赞比亚矿区(Kabwe和Chingola)和对照区(Lusaka)收集了野生黑鼠(Rattus sp.)，比较了它们组织中的金属和金属硫蛋白(MT)水平。此外，我们还对实验室褐家鼠(Rattus norvegicus)进行了为期一年的土壤重金属污染试验，以确定土壤污染对金属的积累因素和影响。现场和实验室研究结果表明，金属污染土壤引起大鼠体内MT-2 mRNA表达水平升高等生物反应。

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Metal contaminated soil from mining area caused metal accumulation and biological responses in rats.

In order to assess the effects of metal contamination on wildlife, we collected wild black rats (Rattus sp.) from mining areas (Kabwe and Chingola) and a control area (Lusaka) in Zambia and compared metal and metallothionein (MT) levels in their tissues. Furthermore, we exposed metal-contaminated soil from Kabwe to laboratory Wistar rats (Rattus norvegicus) for one year in order to determine the accumulation factors and effects of metals caused by soil exposure. Results of both the field and laboratory studies suggested that metal-contaminated soil caused accumulation and biological responses such as elevation of MT-2 mRNA expression levels in rats.

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来源期刊

Japanese Journal of Veterinary Research 农林科学-兽医学

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： The Japanese Journal of Veterinary Research (JJVR) quarterly publishes peer-reviewed articles on all aspects of veterinary science. JJVR was originally published as a “University Journal” of veterinary science at Hokkaido University from more than 60 years ago. Currently, JJVR, is Japan’s leading scientific veterinary journal, and provides valuable information for the development of veterinary science by welcoming contributions from researchers worldwide. JJVR offers online submission for Regular Papers, Short Communications, and Review Articles that are unpublished and not being considered for publication elsewhere. Research areas include: Anatomy, Physiology, Biochemistry, Pharmacology, Microbiology, Infectious diseases, Parasitology, Laboratory Animal Science and Medicine, Internal Medicine, Surgery, Pathology, Theriogenology, Molecular Medicine, Public Health, Radiation Biology, Toxicology, Wildlife Biology and Medicine, Veterinary Hygiene, The other fields related to veterinary science.