[胰岛素抵抗与代谢综合征成分,按性别和青春期阶段分析]。

Eliane Rodrigues de Faria, Franciane Rocha de Faria, Sylvia do Carmo Castro Franceschini, Maria do Carmo Gouveia Peluzio, Luciana Ferreira da Rocha Sant Ana, Juliana Farias de Novaes, Sônia Machado Rocha Ribeiro, Andréia Queiroz Ribeiro, Silvia Eloiza Priore
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引用次数: 16

摘要

目的:分析代谢综合征各组成部分对胰岛素抵抗的影响,按性别和青春期分期进行分析。研究对象和方法:对800名10 ~ 19岁青少年的生化、临床、生活方式和身体成分进行了评价,这些青少年来自巴西、巴西、巴西和巴西,年龄分别为10 ~ 13岁、14 ~ 16岁和17 ~ 19岁。结果:胰岛素抵抗和代谢综合征发生率分别为10.3%和3.4%。在初始阶段,血脂异常、中度高尿酸血症和体脂过多的发生率较高。女性在血脂异常、体脂过多和胰岛素抵抗方面的患病率较高,而男性在低高密度脂蛋白、高尿酸血症和血压变化方面的患病率较高。与其他阶段相比,处于初始阶段的人总胆固醇、低密度脂蛋白、高密度脂蛋白、甘油三酯、空腹血糖和腰臀比水平更高,坐着的时间更短,吃饭的时间更多(p < 0.05)。根据性别调整后的最终模型在青春期的每个阶段都是不同的。结论:胰岛素抵抗与身体成分不足、生化水平和生活方式有关,是青春期各阶段不同的相关因素。
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[Insulin resistance and components of metabolic syndrome, analysis by gender and stage of adolescence].

Objective: To analyze the influence of metabolic syndrome components in insulin resistance, by gender and adolescence phase.

Subjects and methods: We evaluated biochemical, clinical, lifestyle and body composition data of 800 adolescents from 10 to 19 years old, from both genders, from Viçosa, MG/Brasil, and there was the division by stage: early (10 to 13 years), intermediate (14 to 16 years) and late (17 to 19 years).

Results: 10.3 and 3.4% had, respectively, insulin resistance and metabolic syndrome. In the initial phase there was a higher prevalence of dyslipidemia and intermediate hyperuricemia and excess body fat. Females had a higher prevalence of dyslipidemia, excess body fat and insulin resistance and higher male prevalence of low HDL, hyperuricemia and blood pressure changes. Those from the initial phase had higher levels of total cholesterol, LDL, HDL, triglycerides, fasting glucose and waist/hip ratio, stayed less time sitting and had more meals (p < 0.05) in relation to other phases. The final model, adjusted for gender, was different for each phase of adolescence.

Conclusions: Insulin resistance is associated with inadequate body composition, in biochemical levels and lifestyle, being the factors associated different in each phase of adolescence.

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