MCI、阿尔茨海默病和健康对照组的日常活动能力。

IF 0.8 Q4 PSYCHOLOGY, DEVELOPMENTAL GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry Pub Date : 2015-12-01 Epub Date: 2015-11-26 DOI:10.1024/1662-9647/a000136
Justina Avila, Amina Flowers, Travis M Scott, Jill Quilici, Liana G Apostolova, Ellen Woo, John Ringman, Jill Razani
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引用次数: 0

摘要

轻度认知障碍(MCI)是痴呆症的一种危险状态。本研究评估了 MCI 患者(有记忆障碍 [aMCI] 和无记忆障碍 [naMCI])相对于阿尔茨海默病(AD)患者和健康对照组(NC)的日常功能。对 20 名阿尔茨海默病患者、14 名无症状阿尔茨海默病患者、12 名无症状阿尔茨海默病患者和 30 名健康对照者进行了功能状态直接评估(DAFS)。在所有 DAFS 分量表上,注意力缺失症组的表现均差于所有组别。aMCI 组在购物分量表上的表现比对照组差,而 naMCI 组仅在自由回忆购物上的表现比对照组差。最后,DAFS 分量表很好地区分了 AD 组和 aMCI 组,但只有识别购物才能区分 naMCI 和 aMCI 患者。这些研究结果表明,周身ADL缺陷可区分MCI和AD的亚型。
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Daily Activity Abilities in MCI, Alzheimer's Disease, and Healthy Controls.

Mild cognitive impairment (MCI) is a risk state for dementia. The present study assessed daily functioning in MCI individuals (amnestic [aMCI] and nonamnestic [naMCI]) relative to those with Alzheimer's disease (AD) and healthy controls (NC). Twenty AD participants, 14 aMCI, 12 naMCI, and 30 healthy controls were administered the Direct Assessment of Functional Status (DAFS). The AD group performed poorer than all groups on all DAFS subscales. The aMCI group performed poorer than controls on the shopping subtests, while the naMCI group performed poorer than controls on only the free recall shopping. Finally, DAFS subscales discriminated the AD and aMCI groups well, but only recognition shopping discriminated between naMCI and aMCI individuals. These findings suggest that circumscribed ADL deficits distinguish subtypes of MCI and AD.

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