[侧脑室脉络膜丛室管膜和上皮细胞中的细胞接触蛋白-连环蛋白]。

O V Kirik, D A Sufieyva, A V Nazarenkova, D E Korzhevskiy
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引用次数: 0

摘要

本研究的目的是研究细胞接触蛋白-连环蛋白在脑侧脑室脉络膜丛和室管膜中的分布模式。本研究采用针对β -连环蛋白的多克隆抗体对Wistar大鼠(n = 10)的大脑额叶进行了研究。用透射光显微镜和激光共聚焦显微镜对所得制剂进行了分析。为了研究β -连环蛋白在不同投影中的分布,我们进行了三维重建。研究表明该蛋白在室管膜和脉络膜丛的分布模式不同。与室管膜不同,在脉络膜丛细胞中,β -连环蛋白的分布方式与在简单上皮组织中相同(在细胞的基底和外侧边缘)。这可能表明室管膜和脉络膜丛上皮的组织属性不同,尽管它们有共同的起源。
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[CELL CONTACT PROTEIN BETA-CATENIN IN EPENDYMAL AND EPITHELIAL CELLS OF THE CHOROID PLEXUS OF THE CEREBRAL LATERAL VENTRICLES].

The purpose of this study was to examine the distribution pattern of cellular contacts protein beta-catenin in the choroid plexus and ependyma of lateral ventricles of the brain. The study was conducted on frontal sections of the brain of Wistar rats (n = 10) using polyclonal antibodies against beta-catenin. The obtained preparations were analyzed by microscopy in transmitted light and using confocal laser microscopy. To study the distribution of beta-catenin in different projections, three-dimensional reconstruction was performed. The study demonstrated different distribution patterns of this protein in ependyma and choroid plexus. Unlike ependyma, in the cells of the choroid plexus beta-catenin was distributed in the same way as in simple epithelial tissues (on the basal and lateral borders of the cells). This may indicate different tissue attribution of the ependyma and the choroid plexus epithelium, despite their common origin.

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