[实验性肝损伤雌性大鼠子代新生期肠母细胞数量]。

G V Briukhin, M L Sizonenko
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引用次数: 0

摘要

在苏木精-伊红染色的一系列睾丸组织学切片上,使用形态测量仪测量了新生大鼠幼崽曲精小管中生精细胞和支持细胞(支持细胞)的总数。实验组由雌性所生的大鼠组成,这些大鼠具有各种来源的实验性肝损伤——自身免疫性(n = 33)、毒性(n = 32)、酒精性(n = 12)和药物性(n = 27)。对照组为正常母鼠出生的幼鼠(n = 14)。实验大鼠的支持细胞总数有增加和减少的趋势。在大多数实验组动物中,反映生精细胞数量与促生细胞数量之比的促生细胞指数均下降。
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[SUSTENTOCYTE NUMBERS IN THE NEONATAL PERIOD IN THE OFFSPRING OF FEMALE RATS WITH EXPERIMENTAL LIVER DAMAGE].

On serial histological sections of the testes, stained with hematoxylin-eosin, using a morphometric device, the total numbers of spermatogenic cells and sustentocytes (Sertoli cells) were measured in the convoluted seminiferous tubules of neonatal rat pups. Experimental groups consisted of rats born from females with experimental liver damage of various origins--autoimmune (n = 33), toxic (n = 32), alcoholic (n = 12), and medicinal (n = 27). The control group included pups born from normal female rats (n = 14). In experimental rats both increase and decrease of the total number of sustentocytes was detected. In the animals of most of the experimental groups, sustentocyte cell index reflecting the ratio of the number of spermatogenic cells and sustentocytes, was decreased.

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