尼日利亚人肥胖和阻塞性睡眠呼吸暂停的风险。

Journal of Medicine in the Tropics Pub Date : 2017-07-01 Epub Date: 2017-11-15 DOI:10.4103/jomt.jomt_17_17
Maxwell O Akanbi, Patricia A Agaba, Obianuju B Ozoh, Amaka N Ocheke, Zumnan M Gimba, Christiana O Ukoli, Emmanuel I Agaba
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引用次数: 14

摘要

背景:肥胖对阻塞性睡眠呼吸暂停(OSA)的影响在尼日利亚很少被描述。我们的目的是比较尼日利亚城市肥胖和非肥胖成年人之间的OSA风险。材料与方法:采用横断面分析研究。与会者接受了世界卫生组织非传染性疾病调查表的采访。采用STOP-BANG问卷进行OSA风险评估。STOP-BANG问卷总分≥3分表明存在OSA风险,总分≥5分表明存在OSA高风险。肥胖定义为身体质量指数(BMI) >30 kg/m2。使用卡方和逻辑回归模型检验肥胖与OSA的关系,以控制混杂因素。结果:调查对象744人,平均年龄44岁(标准差10)。共有206人(27.7%,95%可信区间(CI) 24.46 ~ 30.9)为肥胖(BMI≥30 kg/m2)。共有307人(41.3%,95% CI 37.7-44.9)在STOP-BANG问卷上得分≥3分,而37人(4.9%,95% CI 3.6-6.7)得分≥5分。肥胖者多于非肥胖者[57.8%(119/206)比34.9%(188/538)]符合OSA危险标准(P < 0.001)。同样,与非肥胖者相比,更多的肥胖者[10.3%(21/206)]符合高危OSA标准[3% (16/538)];P < 0.001。在调整吸烟和饮酒的logistic回归模型中,BMI >35 kg/m2的人与BMI在18.5-24.99之间的人相比,OSA风险的几率为15.76 (95% CI 7.44-33.9)。结论:肥胖和阻塞性睡眠呼吸暂停在尼日利亚可能比先前预测的更为普遍。肥胖单独增加了这一人群的OSA风险。
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Obesity and obstructive sleep apnea risk among Nigerians.

Background: The contribution of obesity to obstructive sleep apnea (OSA) is poorly described in Nigeria. We aimed to compare OSA risk between obese and nonobese adults in urban Nigeria.

Materials and methods: An analytic cross-sectional study was conducted. Participants were interviewed using the World Health Organization Non-Communicable Disease questionnaire. OSA risk assessment was performed using the STOP-BANG questionnaire. A total score of ≥3 on the STOP-BANG questionnaire indicated OSA risk, whereas a score ≥5 indicated high OSA risk. Obesity was defined as body mass index (BMI) >30 kg/m2. Relationship between obesity and OSA was tested using chi-square and logistic regression models used to control for confounding factors.

Results: There were 744 respondents, with a mean age of 44 (standard deviation 10) years. A total of 206 [27.7%, 95% confidence interval (CI) 24.46-30.9] respondents were obese (BMI ≥30 kg/m2). A total of 307 (41.3%, 95% CI 37.7-44.9) respondents scored ≥3 on the STOP-BANG questionnaire, whereas 37 (4.9%, 95% CI 3.6-6.7) scored ≥5. More number of obese than nonobese [57.8% (119/206) versus 34.9% (188/538)] respondents met the criteria for OSA risk (P < 0.001). Similarly, more obese persons [10.3% (21/206)] met the criteria for high-risk OSA compared to the nonobese [3% (16/538)]; P < 0.001. In logistic regression models adjusted for cigarette smoking and alcohol consumption, the odds for OSA risk was 15.76 (95% CI 7.44-33.9) in persons with BMI >35 kg/m2 compared to those with a BMI range of 18.5-24.99.

Conclusion: Obesity and OSA may be more prevalent in Nigeria than previously predicted. Obesity independently increased OSA risk in this population.

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