Marc N G de Mul, Tanya Uddin, Xi Yan, Amber Hubschmitt, Björn Klotz, Wendy Kin Man Chan
{"title":"使用护肤聚合物减少面部皱纹大小,增加皮肤紧致度。","authors":"Marc N G de Mul, Tanya Uddin, Xi Yan, Amber Hubschmitt, Björn Klotz, Wendy Kin Man Chan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Many cosmetic polymers shrink on drying, producing a tensile force if coated on a substrate. This tensile force can be used to smoothen wrinkles and pores in facial skin. In this study, we evaluated two polymers, a polyvinylpyrrolidone (PVP) and a polyacrylate, for skin tightening properties. We conducted a double-blinded, placebo-controlled and randomized clinical study with 32 female volunteers aged 35-65 years who perceived themselves to have a loss of skin elasticity. Both polymers were formulated in a model cosmetic emulsion with hydrogenated polyisobutene as the oil phase. We measured skin firmness and tightening parameters at baseline and after each product application. Also, facial images were recorded with a fringe projection instrument. The firming measurements indicated that both polymers instantly tightened facial skin, whereas the placebo product offered no significant tightening benefit. However, in clinical evaluation, only the polyacrylate polymer produced statistically significant improvements in wrinkle size and skin firmness on the face without significant consumer use complaints such as tackiness. We concluded that skin care products using PVP and polyacrylates have the potential to offer immediate and visible benefits to consumers with aged skin.</p>","PeriodicalId":15523,"journal":{"name":"Journal of cosmetic science","volume":"69 2","pages":"131-143"},"PeriodicalIF":0.2000,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reducing Facial Wrinkle Size and Increasing Skin Firmness Using Skin Care Polymers.\",\"authors\":\"Marc N G de Mul, Tanya Uddin, Xi Yan, Amber Hubschmitt, Björn Klotz, Wendy Kin Man Chan\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Many cosmetic polymers shrink on drying, producing a tensile force if coated on a substrate. This tensile force can be used to smoothen wrinkles and pores in facial skin. In this study, we evaluated two polymers, a polyvinylpyrrolidone (PVP) and a polyacrylate, for skin tightening properties. We conducted a double-blinded, placebo-controlled and randomized clinical study with 32 female volunteers aged 35-65 years who perceived themselves to have a loss of skin elasticity. Both polymers were formulated in a model cosmetic emulsion with hydrogenated polyisobutene as the oil phase. We measured skin firmness and tightening parameters at baseline and after each product application. Also, facial images were recorded with a fringe projection instrument. The firming measurements indicated that both polymers instantly tightened facial skin, whereas the placebo product offered no significant tightening benefit. However, in clinical evaluation, only the polyacrylate polymer produced statistically significant improvements in wrinkle size and skin firmness on the face without significant consumer use complaints such as tackiness. We concluded that skin care products using PVP and polyacrylates have the potential to offer immediate and visible benefits to consumers with aged skin.</p>\",\"PeriodicalId\":15523,\"journal\":{\"name\":\"Journal of cosmetic science\",\"volume\":\"69 2\",\"pages\":\"131-143\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2018-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cosmetic science\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cosmetic science","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Reducing Facial Wrinkle Size and Increasing Skin Firmness Using Skin Care Polymers.
Many cosmetic polymers shrink on drying, producing a tensile force if coated on a substrate. This tensile force can be used to smoothen wrinkles and pores in facial skin. In this study, we evaluated two polymers, a polyvinylpyrrolidone (PVP) and a polyacrylate, for skin tightening properties. We conducted a double-blinded, placebo-controlled and randomized clinical study with 32 female volunteers aged 35-65 years who perceived themselves to have a loss of skin elasticity. Both polymers were formulated in a model cosmetic emulsion with hydrogenated polyisobutene as the oil phase. We measured skin firmness and tightening parameters at baseline and after each product application. Also, facial images were recorded with a fringe projection instrument. The firming measurements indicated that both polymers instantly tightened facial skin, whereas the placebo product offered no significant tightening benefit. However, in clinical evaluation, only the polyacrylate polymer produced statistically significant improvements in wrinkle size and skin firmness on the face without significant consumer use complaints such as tackiness. We concluded that skin care products using PVP and polyacrylates have the potential to offer immediate and visible benefits to consumers with aged skin.
期刊介绍:
The JOURNAL OF COSMETIC SCIENCE (JCS) publishes papers concerned with cosmetics, cosmetic products, fragrances, their formulation and their effects in skin care or in overall consumer well-being, as well as papers relating to the sciences underlying cosmetics, such as human skin physiology, color physics, physical chemistry of colloids and emulsions, or psychological effects of olfaction in humans. Papers of interest to the cosmetic industry and to the understanding of the cosmetic markets are also welcome for publication.