atSNPInfrastructure,一项搜索数十亿条记录的案例研究,同时为云提供商节省了大量成本。

Christopher Harrison, Sündüz Keleş, Rebecca Hudson, Sunyoung Shin, Inês Dutra
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摘要

我们探索了一个数据库存储引擎的可行性,该引擎包含多达3070亿个用于在线访问的遗传单核苷酸多态性(SNP)。我们评估了数据库存储引擎,并利用数据集大小、信息增益、成本和硬件限制等因素实现了解决方案。我们的解决方案为探索人类基因组中SNP的研究人员提供了一个可扩展存储和查询能力的全功能模型。我们通过构建物理基础设施并将最终成本与主要云提供商进行比较来解决可扩展性问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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atSNPInfrastructure, a case study for searching billions of records while providing significant cost savings over cloud providers.

We explore the feasibility of a database storage engine housing up to 307 billion genetic Single Nucleotide Polymorphisms (SNP) for online access. We evaluate database storage engines and implement a solution utilizing factors such as dataset size, information gain, cost and hardware constraints. Our solution provides a full feature functional model for scalable storage and query-ability for researchers exploring the SNP's in the human genome. We address the scalability problem by building physical infrastructure and comparing final costs to a major cloud provider.

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