[健康成人和早期精神分裂症患者脑皮层灰质形态与执行功能和处理速度的关系]。

IF 0.2 4区 医学 Q4 NEUROSCIENCES Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova Pub Date : 2016-07-01
M V Alfimoval, A S Tomyshev, I S Lebedeva, T A Akhadov, N A Semenoval, V G Kaleda
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引用次数: 0

摘要

13名精神分裂症男性患者和18名年龄匹配的健康男性接受了结构磁共振成像,并完成了包括转换条件的Stroop任务。与对照组相比,在中性状态下,患者的颜色命名速度减慢,额叶和颞叶区域的灰质体积和厚度减少。在健康受试者中,颜色命名时间与左楔脑灰质体积呈负相关。在精神分裂症组中,颜色命名时间与右半球额下回皮层厚度呈正相关。这些结果表明,在精神分裂症的早期阶段,结构-功能关系发生了变化。
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[Relationship of Executive Functions and Processing Speed with Cortical Gray Matter Morphometry in Healthy Adults and at The Early Stages of Schizophrenia].

13 male patients with schizophrenia and 18 age-matched healthy men underwent structural magnetic reso- nance imaging and completed the Stroop task which included the switching condition. As compared to con- trols, the patients showed slowing of color naming in the neutral condition and a reduction ofgray matter vol- ume and thickness in the frontal and temporal areas. In healthy subjects, the time of color naming was neg- atively correlated with gray matter volume in the left cuneus. In the schizophrenia group, there was a positive correlation between the time of color naming and cortical thickness in the middle and inferior frontal gyri of the right hemisphere. These results indicate a change in structural-functional relationships at the early stages of schizophrenia.

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来源期刊
CiteScore
0.70
自引率
33.30%
发文量
9
审稿时长
6-12 weeks
期刊介绍: Information not localized
期刊最新文献
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