[健康受试者与言语障碍患者言语与空间思维脑活动的比较分析]。

IF 0.2 4区 医学 Q4 NEUROSCIENCES Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I P Pavlova Pub Date : 2016-05-01
O V Martynova, G V Portnova, V V Balaev, A M Ivanitsky
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引用次数: 0

摘要

我们分析了15名健康受试者和9名构音障碍或轻度感觉运动失语症患者在空间和语言任务中使用功能磁共振成像(fMRI)测量的特定大脑活动。在健康被试中,言语思维的特征是在Brodmann区19和Broca区激活,而空间思维的特征是在双侧颞-枕-顶叶区、左岛区、左视野17和18区激活。在言语障碍患者中,与健康受试者相比,特定类型任务的网络分布随着大脑区域的失活而发生了显著变化。尽管没有认知障碍的临床表现,但与一组健康受试者相比,患者解决口头任务的平均时间明显更高,正确答案的百分比也更少。
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[Comparative Analysis of the Brain Activity during Verbal and Spatial Thinking in Healthy Subjects and Patients with Speech Disorders].

We analyzed the specific brain activity, measured by fMRI in spatial and verbal tasks, in 15 healthy sub- jects and in 9 patients with dysarthria or mild sensorimotor aphasia. In healthy participants, verbal thinking was characterized by activation in Brodmann area 19 and Broca area while specific activation for spatial thinking was observed in bilateral temporal-occipital-parietal areas, left insula, left visual fields 17 and 18. In patients with impaired speech, this distribution of networks specific to a particular type of task underwent significant changes with deactivation of the brain areas, as compared to healthy subjects. Despite the absence of clinical manifestations of cognitive impairment, the average time .to solve verbal tasks was significantly higher, and the percentage of correct answers was less in patients as compared to these values for a group of healthy subjects.

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来源期刊
CiteScore
0.70
自引率
33.30%
发文量
9
审稿时长
6-12 weeks
期刊介绍: Information not localized
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