预防措施对COVID-19传播影响的数学建模:以坦桑尼亚为例

IF 1.8 4区 数学 Q3 ECOLOGY Journal of Biological Dynamics Pub Date : 2020-12-01 DOI:10.1080/17513758.2020.1823494
Abdul-Rahman J Mumbu, Alfred K Hugo
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引用次数: 25

摘要

2019年12月,COVID-19首次在中国武汉市爆发,随后迅速在全球蔓延。本文提出了一个数学模型,用于研究坦桑尼亚在人口戴口罩和住院服务的情况下其传播动力学。确定了无病平衡和地方性平衡,随后进行了局部和全局稳定。无病平衡点的局部稳定性采用迹迹行列式方法,无病平衡点和地方病平衡点的全局稳定性采用Lyapunov函数技术。确定了基本复制数R0,其数值结果显示,在佩戴口罩并提供药物治疗或住院治疗作为预防传播措施的情况下,R0=0.698,而在没有这些措施的情况下,R0=3.8。这支持了无病平衡点E0在R01时渐近稳定,而地方病平衡点E *在R0>1时全局渐近稳定的解析解。因此,本文证明了COVID-19患者佩戴口罩和住院治疗的必要性,以遏制疾病向人群传播。
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Mathematical modelling on COVID-19 transmission impacts with preventive measures: a case study of Tanzania.

The outbreak of COVID-19 was first experienced in Wuhan City, China, during December 2019 before it rapidly spread over globally. This paper has proposed a mathematical model for studying its transmission dynamics in the presence of face mask wearing and hospitalization services of human population in Tanzania. Disease-free and endemic equilibria were determined and subsequently their local and global stabilities were carried out. The trace-determinant approach was used in the local stability of disease-free equilibrium point while Lyapunov function technique was used to determine the global stability of both disease-free and endemic equilibrium points. Basic reproduction number, R0 , was determined in which its numerical results revealed that, in the presence of face masks wearing and medication services or hospitalization as preventive measure for its transmission, R0=0.698 while in their absence R0=3.8 . This supports its analytical solution that the disease-free equilibrium point E0 is asymptotically stable whenever R0<1 , while endemic equilibrium point E is globally asymptotically stable for R0>1 . Therefore, this paper proves the necessity of face masks wearing and hospitalization services to COVID-19 patients to contain the disease spread to the population.

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来源期刊
Journal of Biological Dynamics
Journal of Biological Dynamics ECOLOGY-MATHEMATICAL & COMPUTATIONAL BIOLOGY
CiteScore
4.90
自引率
3.60%
发文量
28
审稿时长
33 weeks
期刊介绍: Journal of Biological Dynamics, an open access journal, publishes state of the art papers dealing with the analysis of dynamic models that arise from biological processes. The Journal focuses on dynamic phenomena at scales ranging from the level of individual organisms to that of populations, communities, and ecosystems in the fields of ecology and evolutionary biology, population dynamics, epidemiology, immunology, neuroscience, environmental science, and animal behavior. Papers in other areas are acceptable at the editors’ discretion. In addition to papers that analyze original mathematical models and develop new theories and analytic methods, the Journal welcomes papers that connect mathematical modeling and analysis to experimental and observational data. The Journal also publishes short notes, expository and review articles, book reviews and a section on open problems.
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